The 'EF-hand'Ca2+-binding motif plays an essential role in eukaryotic cellular signalling,
and the proteins containing this motif constitute a large and functionally diverse family. The …

The calcium binding proteins of the EF-hand super-family are involved in the regulation of all
aspects of cell function. These proteins exhibit a great diversity of composition, structure …

This Handbook on Metalloproteins focuses on the available structural information of proteins
and their metal ion coordination spheres. It centers on the metal ions indispensable for life …

The distal tubule reabsorbs∼ 10% of the filtered Mg2+, but this is 70–80% of that delivered
from the loop of Henle. Because there is little Mg2+ reabsorption beyond the distal tubule …

Introduction 3. Morphology of matrix vesicles (MVs) 3.1. Conventional transmission electron
microscopy 3.2. Cryofixation, freeze-substitution electron microscopy 3.3. Freeze-fracture …

The growing database of three-dimensional structures of EF-hand calcium-binding proteins
is revealing a previously unrecognized variability in the coformations and organizations of …

Calcium ion is a versatile messenger in many cell-signaling processes. To achieve their
functions, calcium-binding proteins selectively bind Ca2+ against a background of …

The Ca2+-binding helix–loop–helix structural motif called “EF-hand” is a common building
block of a large family of proteins that function as intracellular Ca2+-receptors. These …

Assigning proteins with functions based on the 3‐D structure requires high‐speed
techniques to make a systematic survey of protein structures. Calcium regulates many …

Current ion models in molecular mechanics are simple spheres, and their interactions are
solely determined from the van der Waals radius of the sphere and the total charge. Here …