pH-responsive nanocarriers in cancer therapy

NM AlSawaftah, NS Awad, WG Pitt, GA Husseini - Polymers, 2022 - mdpi.com
A number of promising nano-sized particles (nanoparticles) have been developed to
conquer the limitations of conventional chemotherapy. One of the most promising methods is …

Dual-targeting and stimuli-triggered liposomal drug delivery in cancer treatment

N AlSawaftah, WG Pitt, GA Husseini - ACS pharmacology & …, 2021 - ACS Publications
The delivery of chemotherapeutics to solid tumors using smart drug delivery systems
(SDDSs) takes advantage of the unique physiology of tumors (ie, disordered structure, leaky …

Prospects of topoisomerase inhibitors as promising anti-cancer agents

PA Yakkala, NR Penumallu, S Shafi, A Kamal - Pharmaceuticals, 2023 - mdpi.com
Topoisomerases are very important enzymes that regulate DNA topology and are vital for
biological actions like DNA replication, transcription, and repair. The emergence and spread …

Co-crystal nanoarchitectonics as an emerging strategy in attenuating cancer: Fundamentals and applications

P Kumbhar, K Kolekar, C Khot, S Dabhole… - Journal of Controlled …, 2023 - Elsevier
Cancer ranks as the second foremost cause of death in various corners of the globe. The
clinical uses of assorted anticancer therapeutics have been limited owing to the poor …

Pleurotus highking mushrooms potentiate antiproliferative and antimigratory activity against triple-negative breast cancer cells by suppressing Akt signaling

MA Haque, ASMA Reza, MS Nasrin… - Integrative cancer …, 2020 - journals.sagepub.com
In this study, we evaluated the antiproliferative and antimetastatic effects of the Pleurotus
highking mushroom on the human triple-negative breast cancer cell lines MDA-MB-231 and …

Internalized functional DNA aptamers as alternative cancer therapies

ML Marshall, KM Wagstaff - Frontiers in Pharmacology, 2020 - frontiersin.org
Despite major advances, cancer remains one of the largest burdens of disease worldwide.
One reason behind this is that killing tumor cells without affecting healthy surrounding tissue …

The Use of Microspheres for Cancer Embolization Therapy: Recent Advancements and Prospective

NA Nuzulia, T Mart, I Ahmed… - ACS Biomaterials Science …, 2024 - ACS Publications
Embolization therapy involving biomaterials has improved the therapeutic strategy for most
liver cancer treatments. Developing biomaterials as embolic agents has significantly …

Botanical Sources, Pharmacokinetics, and Therapeutic Efficacy of Palmatine and Its Derivatives in the Management of Cancer: A Comprehensive Mechanistic …

MI Jahan Oni, MS Bhuia, R Chowdhury… - Journal of Food …, 2024 - Wiley Online Library
Natural compounds and their derivatives have been identified as valuable sources of
therapeutic ingredients for cancer treatment. The naturally occurring phytochemical …

A potent formula against triple‐negative breast cancer—sorafenib‐carbon nanotubes‐folic acid: Targeting, apoptosis triggering, and bioavailability enhancing

HMS Nabawi, AZ Abdelazem… - Biotechnology and …, 2023 - Wiley Online Library
Triple‐negative breast cancer (TNBC) has short survival rates. This study aimed to prepare a
novel formula of sorafenib, carbon nanotubes (CNTs), and folic acid to be tested as a drug …

REVOLUTIONIZING CANCER TREATMENT: THE ROLE OF CHITOSAN NANOPARTICLES IN THERAPEUTIC ADVANCEMENTS

AK Lunawat, S Thakur, BD Kurmi, GD Gupta… - Journal of Drug Delivery …, 2024 - Elsevier
Cancer poses a significant global health threat, with millions of new cases and deaths
annually reported. The traditional chemotherapy faces challenges due to poor drug …