New psychoactive substances: a review and updates

A Shafi, AJ Berry, H Sumnall… - Therapeutic …, 2020 - journals.sagepub.com
New psychoactive substances (NPS) are a heterogeneous group of substances. They are
associated with a number of health and social harms on an individual and societal level …

Serotonin toxicity of serotonergic psychedelics

B Malcolm, K Thomas - Psychopharmacology, 2022 - Springer
Objectives A critical evaluation of the scientific literature is necessary to delineate the risks of
ST when combining psychedelics with available serotonergic pharmacotherapy options …

An update on the implications of new psychoactive substances in public health

AY Simão, M Antunes, E Cabral, P Oliveira… - International journal of …, 2022 - mdpi.com
The emergence of new psychoactive substances has earned a great deal of attention, and
several reports of acute poisoning and deaths have been issued involving, for instance …

Chemical classification of new psychoactive substances (NPS)

F Zapata, JM Matey, G Montalvo, C García-Ruiz - Microchemical Journal, 2021 - Elsevier
This work comprehensively reviews some fundamental concepts about drugs, especially
focusing on new psychoactive substances (NPS), and their typical classifications based on …

Insights into biased signaling at cannabinoid receptors: synthetic cannabinoid receptor agonists

E Wouters, J Walraed, SD Banister, CP Stove - Biochemical pharmacology, 2019 - Elsevier
Abstract Cannabinoid receptors type 1 (CB 1) and type 2 (CB 2) are promising targets for a
number of diseases, including obesity, neuropathic pain, and multiple sclerosis, among …

Synthetic cathinones–From natural plant stimulant to new drug of abuse

E Pieprzyca, R Skowronek, Ľ Nižnanský… - European Journal of …, 2020 - Elsevier
As recreational substances, synthetic cathinones started to be used at the beginning of the
21st century. There is still limited data on these compounds, introduced to the illicit drug …

The rise of new psychoactive substances and psychiatric implications: A wide‐ranging, multifaceted challenge that needs far‐reaching common legislative strategies

R Rinaldi, G Bersani, E Marinelli… - Human …, 2020 - Wiley Online Library
The ever‐growing number of novel psychoactive substances (NPS) that have been
surfacing globally, as well as related changes in drug abuse trends, undoubtedly constitute …

[HTML][HTML] Cardiotoxicity screening of illicit drugs and new psychoactive substances (NPS) in human iPSC-derived cardiomyocytes using microelectrode array (MEA) …

A Zwartsen, T De Korte, P Nacken… - Journal of molecular and …, 2019 - Elsevier
The use of recreational drugs, including new psychoactive substances (NPS), is paralleled
by emergency department visits of drug users with severe cardiotoxicity. Drug-induced …

Novel psychoactive phenethylamines: impact on genetic material

V Cocchi, S Gasperini, P Hrelia, M Tirri, M Marti… - International Journal of …, 2020 - mdpi.com
Psychedelic and stimulating phenethylamines belong to the family of new psychoactive
substances (NPS). The acute toxicity framework has begun to be investigated, while studies …

In vitro structure–activity relationship determination of 30 psychedelic new psychoactive substances by means of β-arrestin 2 recruitment to the serotonin 2A receptor

E Pottie, A Cannaert, CP Stove - Archives of toxicology, 2020 - Springer
Serotonergic psychedelics, substances exerting their effects primarily through the serotonin
2A receptor (5-HT 2A R), continue to comprise a substantial portion of reported new …