It is well known that only a small proportion of the human genome code for proteins; the rest
belong to the family of RNAs that do not code for protein and are known as non-coding …

Suicide is a multifaceted and poorly understood clinical outcome, and there is an urgent
need to advance research on its phenomenology and etiology. Epidemiological studies …

Objective: The authors sought to study the transcriptomic and genomic features of completed
suicide by parsing the method chosen, to capture molecular correlates of the distinctive …

Background RNA-directed regulation of epigenetic processes has recently emerged as an
important feature of mammalian differentiation and development. Perturbation of this …

Worldwide, one person dies every 40 seconds by suicide, a potentially preventable tragedy.
A limiting step in our ability to intervene is the lack of objective, reliable predictors. We have …

The biological fingerprint of environmental adversity may be key to understanding health
and disease, as it encompasses the damage induced as well as the compensatory reactions …

The human genome project has revolutionized our understanding of the underlying
mechanisms in psychiatric disease. It is now abundantly clear that neurobehavioral …

Blood biomarkers may provide a scientifically useful and clinically usable peripheral signal
in psychiatry, as they have been doing for other fields of medicine. Jumping to premature …

The underlying mechanisms of cognitive impairment in diabetes remain incompletely
characterized. Here we show that the autophagic inhibition by 3-methyladenine (3-MA) …

Intracellular protein-protein interactions are dynamic events requiring tightly regulated
spatial and temporal checkpoints. But how are these spatial and temporal cues integrated to …