Mechanistic understanding of lanthipeptide biosynthetic enzymes
Lanthipeptides are ribosomally synthesized and post-translationally modified peptides
(RiPPs) that display a wide variety of biological activities, from antimicrobial to antiallodynic …
(RiPPs) that display a wide variety of biological activities, from antimicrobial to antiallodynic …
[HTML][HTML] New insights into the biosynthetic logic of ribosomally synthesized and post-translationally modified peptide natural products
MA Ortega, WA Van Der Donk - Cell chemical biology, 2016 - cell.com
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a large
group of structurally diverse natural products. Their biological activities and unique …
group of structurally diverse natural products. Their biological activities and unique …
Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB
Lantibiotics are a class of peptide antibiotics that contain one or more thioether bonds. The
lantibiotic nisin is an antimicrobial peptide that is widely used as a food preservative to …
lantibiotic nisin is an antimicrobial peptide that is widely used as a food preservative to …
Discovery, biosynthesis, and engineering of lantipeptides
PJ Knerr, WA Van Der Donk - Annual review of biochemistry, 2012 - annualreviews.org
Aided by genome-mining strategies, knowledge of the prevalence and diversity of
ribosomally synthesized natural products (RNPs) is rapidly increasing. Among these are the …
ribosomally synthesized natural products (RNPs) is rapidly increasing. Among these are the …
RRE-Finder: a genome-mining tool for class-independent RiPP discovery
AM Kloosterman, KE Shelton, GP van Wezel… - Msystems, 2020 - Am Soc Microbiol
Many ribosomally synthesized and posttranslationally modified peptide classes (RiPPs) are
reliant on a domain called the RiPP recognition element (RRE). The RRE binds specifically …
reliant on a domain called the RiPP recognition element (RRE). The RRE binds specifically …
In vitro activity of the nisin dehydratase NisB
N Garg, LMA Salazar-Ocampo… - Proceedings of the …, 2013 - National Acad Sciences
The biosynthesis of several classes of ribosomally synthesized and posttranslationally
modified peptides involves dehydration of serine and threonine residues. For class I …
modified peptides involves dehydration of serine and threonine residues. For class I …
Ribosomally synthesized and post‐translationally modified peptide natural products: New insights into the role of leader and core peptides during biosynthesis
X Yang, WA Van Der Donk - Chemistry–A European Journal, 2013 - Wiley Online Library
Ribosomally synthesized and post‐translationally modified peptides (RiPPs) are a major
class of natural products with a high degree of structural diversity and a wide variety of …
class of natural products with a high degree of structural diversity and a wide variety of …
Structural Analysis of Class I Lanthipeptides from Pedobacter lusitanus NL19 Reveals an Unusual Ring Pattern
Lanthipeptides are ribosomally synthesized and post-translationally modified peptide
natural products characterized by the presence of lanthionine and methyllanthionine cross …
natural products characterized by the presence of lanthionine and methyllanthionine cross …
Aminoacyl-tRNA-utilizing enzymes in natural product biosynthesis
M Moutiez, P Belin, M Gondry - Chemical reviews, 2017 - ACS Publications
Aminoacyl-tRNAs were long thought to be involved solely in ribosome-dependent protein
synthesis and essential primary metabolism processes, such as targeted protein …
synthesis and essential primary metabolism processes, such as targeted protein …
Microbiome‐wide association studies reveal correlations between the structure and metabolism of the rhizosphere microbiome and disease resistance in cassava
L Zhang, J Zhang, Y Wei, W Hu, G Liu… - Plant biotechnology …, 2021 - Wiley Online Library
Cassava is one of the most important staple food crops in tropical regions. To date, an
understanding of the relationship between microbial communities and disease resistance in …
understanding of the relationship between microbial communities and disease resistance in …