The oral administration of therapeutic peptides and proteins is favoured from a patient and
commercial point of view. In order to reach the systemic circulation after oral administration …

Hydrophobic ion pairing has emerged as a method to modulate the solubility of charged
hydrophilic molecules ranging in class from small molecules to large enzymes. Charged …

In the modern world, a number of therapeutic proteins such as vaccines, antigens, and
hormones are being developed utilizing different sophisticated biotechnological techniques …

Polymeric drug-loaded nanoparticles have been extensively studied in the field of drug
delivery. Biodistribution depends on the physicochemical properties of particles, especially …

Peptides and proteins remain poorly bioavailable upon oral administration. One of the most
promising strategies to improve their oral delivery relies on their association with colloidal …

Oral administration of protein drugs is greatly impeded by the lack of drug carriers that can
efficiently overcome the absorption barriers of mucosa tissue, which consists of not only …

Purpose To evaluate the pharmacological activity of insulin-loaded alginate/chitosan
nanoparticles following oral dosage in diabetic rats. Methods Nanoparticles were prepared …

Oral delivery of peptides and proteins remains an attractive alternative to parenteral delivery
and has challenged various attempts at delivery development. Incorporation of new tools …

Phospholipids become increasingly important as formulation excipients and as active
ingredients per se. The present article summarizes particular features of commonly used …

Oral route is the most common route for the delivery of drugs because it is simple to
implement and improves patient compliance and quality of life. However, oral absorption is …