Extracellular vesicles (EVs) are membrane vesicles released by both eukaryotic and
prokaryotic cells; they not only serve physiological functions, such as disposal of cellular …

Sphingolipids, which are components of cellular membranes and organ tissues, can be
synthesized or degraded to modulate cellular responses according to environmental cues …

The central nervous system is characterized by a high content of sphingolipids and by a high
diversity in terms of different structures. Stage-and cell-specific sphingolipid metabolism and …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-
19 pandemic with severe consequences for afflicted individuals and the society as a whole …

The large surfaces of gastrointestinal (GI) organs are well adapted to their diverse tasks of
selective nutritional uptake and defense against the external environment. To maintain a …

Recurrent major depressive disorder (rMDD) is a relapsing-remitting disease with high
morbidity and a 5-year risk of recurrence of up to 80%. This was a prospective pilot study to …

Iminosugars are sugar analogues endowed with a high pharmacological potential. The wide
range of biological activities exhibited by these glycomimetics associated with their excellent …

Recently, we highlighted that the ganglioside GM 1 promotes neuroblastoma cells
differentiation by activating the TrkA receptor through the formation of a TrkA–GM 1 …

Background More than 230,000 veterans—about 1/3 of US personnel deployed in the 1990–
1991 Persian Gulf War—developed chronic, multi-symptom health problems now called …

Bisphenol A (BPA) is a well-known endocrine disruptor that has obesogenic properties. We
have previously reported sex-and age-dependent changes in hepatic transcriptome and …