The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

The human skeleton has remarkable regenerative properties, being one of the few
structures in the body that can heal by recreating its normal cellular composition, orientation …

Macrophages are a highly heterogeneous and plastic population of cells that are crucial for
tissue repair and regeneration. This has made macrophages a particularly attractive target …

Macrophages represent heterogeneous cell population with important roles in defence
mechanisms and in homoeostasis. Tissue macrophages from diverse anatomical locations …

Cellular associations in the bone microenvironment are involved in modulating the balance
between bone remodeling and resorption, which is necessary for maintaining a normal bone …

Osteoimmunity is involved in regulating the balance of bone remodeling and resorption, and
is essential for maintaining normal bone morphology. The interaction between immune cells …

Bone metastases are a frequent and severe complication of advanced-stage cancers. Breast
and prostate cancers, the most common malignancies in women and men, respectively …

Objectives Research across many fields of medicine now points towards the clinical
advantages of combining regenerative procedures with platelet-rich fibrin (PRF). This …

Bone healing is a complex physiological process initiated by early regulation of the
inflammatory immunity and entails multiple events including angiogenesis, osteogenic …

Self-maintaining resident macrophages populate all mammalian organs. In addition to their
role as immune sentinels, macrophages perform day-to-day functions essential to tissue …