Choroid plexus Aquaporins in CSF homeostasis and the Glymphatic system: their relevance for Alzheimer's disease

C Municio, L Carrero, D Antequera, E Carro - International Journal of …, 2023 - mdpi.com
The glymphatic system, a fluid-clearance pathway involved in brain waste clearance, is
known to be impaired in neurological disorders, including Alzheimer's disease (AD). For this …

Peripheral immune cells and perinatal brain injury: a double-edged sword?

J Herz, I Bendix, U Felderhoff-Müser - Pediatric research, 2022 - nature.com
Perinatal brain injury is the leading cause of neurological mortality and morbidity in
childhood ranging from motor and cognitive impairment to behavioural and neuropsychiatric …

The choroid plexus acts as an immune cell reservoir and brain entry site in experimental autoimmune encephalomyelitis

I Lazarevic, S Soldati, JA Mapunda, H Rudolph… - Fluids and Barriers of …, 2023 - Springer
The choroid plexus (ChP) has been suggested as an alternative central nervous system
(CNS) entry site for CCR6+ Th17 cells during the initiation of experimental autoimmune …

Structural and functional remodeling of the brain vasculature following stroke

M Freitas-Andrade, J Raman-Nair, B Lacoste - Frontiers in physiology, 2020 - frontiersin.org
Maintenance of cerebral blood vessel integrity and regulation of cerebral blood flow ensure
proper brain function. The adult human brain represents only a small portion of the body …

Choroid plexus epithelium and its role in neurological diseases

R Liu, Z Zhang, Y Chen, J Liao, Y Wang… - Frontiers in Molecular …, 2022 - frontiersin.org
Choroid plexus epithelial cells can secrete cerebrospinal fluid into the ventricles, serving as
the major structural basis of the selective barrier between the neurological system and blood …

Role of SPAK–NKCC1 signaling cascade in the choroid plexus blood–CSF barrier damage after stroke

J Wang, R Liu, MN Hasan, S Fischer, Y Chen… - Journal of …, 2022 - Springer
Background The mechanisms underlying dysfunction of choroid plexus (ChP) blood–
cerebrospinal fluid (CSF) barrier and lymphocyte invasion in neuroinflammatory responses …

Inflammatory hydrocephalus

SM Robert, BC Reeves, A Marlier, PQ Duy… - Child's Nervous …, 2021 - Springer
Reparative inflammation is an important protective response that eliminates foreign
organisms, damaged cells, and physical irritants. However, inappropriately triggered or …

Macrophages on the margin: choroid plexus immune responses

J Cui, H Xu, MK Lehtinen - Trends in neurosciences, 2021 - cell.com
The choroid plexus (ChP), an epithelial bilayer containing a network of mesenchymal,
immune, and neuronal cells, forms the blood–cerebrospinal fluid (CSF) barrier (BCSFB) …

Microglia‐leucocyte axis in cerebral ischaemia and inflammation in the developing brain

A Rayasam, Y Fukuzaki, ZS Vexler - Acta Physiologica, 2021 - Wiley Online Library
Abstract Development of the Central Nervous System (CNS) is reliant on the proper function
of numerous intricately orchestrated mechanisms that mature independently, including …

Danshen-Chuanxiongqin Injection attenuates cerebral ischemic stroke by inhibiting neuroinflammation via the TLR2/TLR4-MyD88-NF-κB Pathway in tMCAO mice

XU Xiao-Jing, L Jin-Bo, JIN Kai-Yu, C Li-Bing… - Chinese Journal of …, 2021 - Elsevier
Abstract Danshen-Chuanxiongqin Injection (DCI) is a commonly used traditional Chinese
medicine for the treatment of cerebral ischemic stroke in China. However, its underlying …