Cellular crosstalk between endothelial and smooth muscle cells in vascular wall remodeling

N Méndez-Barbero, C Gutiérrez-Muñoz… - International Journal of …, 2021 - mdpi.com
Pathological vascular wall remodeling refers to the structural and functional changes of the
vessel wall that occur in response to injury that eventually leads to cardiovascular disease …

Extracellular vesicles, inflammation, and cardiovascular disease

A Akhmerov, T Parimon - Cells, 2022 - mdpi.com
Cardiovascular disease is a leading cause of death worldwide. The underlying mechanisms
of most cardiovascular disorders involve innate and adaptive immune responses, and …

Platelets at the vessel wall in non-thrombotic disease

A Aggarwal, CL Jennings, E Manning… - Circulation …, 2023 - Am Heart Assoc
Platelets are small, anucleate entities that bud from megakaryocytes in the bone marrow.
Among circulating cells, platelets are the most abundant cell, traditionally involved in …

[HTML][HTML] Modulation of immune-inflammatory responses in abdominal aortic aneurysm: emerging molecular targets

H Li, S Bai, Q Ao, X Wang, X Tian, X Li… - Journal of Immunology …, 2018 - hindawi.com
Abdominal aortic aneurysm (AAA), a deadly vascular disease in human, is a chronic
degenerative process of the abdominal aorta. In this process, inflammatory responses and …

Multifaceted role of extracellular vesicles in atherosclerosis

A Konkoth, R Saraswat, C Dubrou, F Sabatier… - Atherosclerosis, 2021 - Elsevier
Extracellular vesicles (EVs) are small vesicles released by the majority of cells in response
to cell activation or death stimuli. They are grouped as small EVs or exosomes, large EVs …

Role of extracellular vesicles as potential diagnostic and/or therapeutic biomarkers in chronic cardiovascular diseases

JL Martin-Ventura, C Roncal, J Orbe… - Frontiers in Cell and …, 2022 - frontiersin.org
Cardiovascular diseases (CVDs) are the first cause of death worldwide. In recent years,
there has been great interest in the analysis of extracellular vesicles (EVs), including …

Beyond macromolecules: extracellular vesicles as regulators of inflammatory diseases

K Das, S Paul, T Mukherjee, A Ghosh, A Sharma… - Cells, 2023 - mdpi.com
Inflammation is the defense mechanism of the immune system against harmful stimuli such
as pathogens, toxic compounds, damaged cells, radiation, etc., and is characterized by …

Exosomes: cell-free therapy for cardiovascular diseases

N He, Y Zhang, S Zhang, D Wang, H Ye - Journal of cardiovascular …, 2020 - Springer
Cardiovascular diseases (CVDs) are an important cause of death and disease worldwide.
Because injured cardiac tissue cannot be repaired itself, it is urgent to develop other …

[HTML][HTML] Effects of ex vivo blood anticoagulation and preanalytical processing time on the proteome content of platelets

ST Yunga, AJ Gower, AR Melrose, MK Fitzgerald… - Journal of Thrombosis …, 2022 - Elsevier
Background Ex vivo assays of platelet function critically inform mechanistic and clinical
hematology studies, where effects of divergent blood processing methods on platelet …

Aortic aneurysms: current pathogenesis and therapeutic targets

MJ Cho, MR Lee, JG Park - Experimental & Molecular Medicine, 2023 - nature.com
Aortic aneurysm is a chronic disease characterized by localized expansion of the aorta,
including the ascending aorta, arch, descending aorta, and abdominal aorta. Although aortic …