[HTML][HTML] Recent Advances in Metal Complexes Based on Biomimetic and Biocompatible Organic Ligands against Leishmaniasis Infections: State of the Art and …

S Jimenez-Falcao, JM Mendez-Arriaga - Inorganics, 2024 - mdpi.com
Leishmaniasis is a complex disease present in a variety of manifestations listed by the World
Health Organization (WHO) as one of the neglected diseases with a worse prognosis if not …

[HTML][HTML] Models for cytotoxicity screening of antileishmanial drugs: what has been done so far?

MBC Brioschi, EM Coser, AC Coelho… - International Journal of …, 2022 - Elsevier
A growing number of studies have demonstrated the in vitro potential of an impressive
number of antileishmanial candidates in the past years. However, the lack of uniformity …

First-Row Transition 7-Oxo-5-phenyl-1, 2, 4-triazolo [1, 5-a] pyrimidine Metal Complexes: Antiparasitic Activity and Release Studies

Á Martín-Montes, S Jimenez-Falcao, S Gómez-Ruiz… - Pharmaceuticals, 2023 - mdpi.com
Leishmaniasis and Chagas disease are still considered neglected illnesses due to the lack
of investment in research, despite the fact that almost one million new cases are reported …

Biological activity of triazolopyrimidine copper (II) complexes modulated by an auxiliary NN-chelating heterocycle ligands

LL Ruta, IC Farcasanu, M Bacalum, M Răileanu… - Molecules, 2021 - mdpi.com
Novel complexes of type [Cu (NN)(dmtp) 2 (OH2)](ClO4) 2· dmtp ((1) NN: 2, 2′-
bipyridine;(2) L: 1, 10-phenantroline and dmtp: 5, 7-dimethyl-1, 2, 4-triazolo [1, 5-a] …

In vitro evaluation of leishmanicidal properties of a new family of monodimensional coordination polymers based on diclofenac ligand

A García-García, JM Mendez-Arriaga… - Polyhedron, 2020 - Elsevier
Some series of isostructural chains with general formula [M (diclof) 2 (H 2 O) 2]·(EtOH) 2
have been obtained from reaction between diclofenac ligand (diclof) and first row transition …

[PDF][PDF] Mărut, escu, L.; Popa, M.; Badea, M.; et al. Biological activity of triazolopyrimidine copper (II) complexes modulated by an auxiliary NN-chelating heterocycle …

LL Ruta, IC Farcasanu, M Bacalum, M Răileanu… - Molecules, 2021 - academia.edu
Staphylococcus aureus (MRSA). Both electron paramagnetic resonance (EPR) and
Saccharomyces cerevisiae studies indicated that the complexes were scavengers rather …

Insights into structure and biological activity of copper (II) and zinc (II) complexes with triazolopyrimidine ligands

A Argăseală, C Maxim, M Badea, L Ioniță… - Molecules, 2022 - mdpi.com
In an attempt to increase the biological activity of the 1, 2, 4-triazolo [1, 5-a] pyrimidine
scaffold through complexation with essential metal ions, the complexes trans-[Cu (mptp) …

[PDF][PDF] Ionit, a

A Argaseala, C Maxim, M Badea - Molecules, 2022 - academia.edu
In an attempt to increase the biological activity of the 1, 2, 4-triazolo [1, 5-a] pyrimidine
scaffold through complexation with essential metal ions, the complexes trans-[Cu (mptp) …

Zinc 1, 2, 4-Triazolo [1, 5-a] Pyrimidine Complexes: Synthesis, Structural Characterization and Their Effect Against Chagas Disease

JM Méndez-Arriaga, E Rubio-Mirallas… - Medicinal …, 2022 - ingentaconnect.com
Background: The World Health Organization catalogues illnesses such as Chagas disease
as neglected diseases, due to the low investment in new drugs to fight them. The search for …

Photoluminescence and in vitro cytotoxicity analysis in a novel mononuclear Zn (II) coordination compound based on bumetanide

A García-García, E Echenique-Errandonea… - Inorganica Chimica …, 2020 - Elsevier
A novel coordination compound based on Zn (II) and bumetanide (Hbum) of general
formulae [Zn (bum) 2 (H 2 O) 2]· 2H 2 O has been synthesized and fully characterized by …