Regulation of the activity of the promoter of RNA‐induced silencing, C3PO

S Sahu, L Williams, A Perez, F Philip, G Caso… - Protein …, 2017 - Wiley Online Library
RNA‐induced silencing is a process which allows cells to regulate the synthesis of specific
proteins. RNA silencing is promoted by the protein C3PO (component 3 of RISC). We have …

Mesenchymal cell differentiation and diseases: involvement of translin/TRAX complexes and associated proteins

M Kasai, R Ishida, K Nakahara… - Annals of the New …, 2018 - Wiley Online Library
Translin and translin‐associated factor X (translin/TRAX) proteins have been implicated in a
variety of cellular activities central to nucleic acid metabolism. Accumulating evidence …

Translin: A multifunctional protein involved in nucleic acid metabolism

A Gupta, VS Pillai, RK Chittela - Journal of Biosciences, 2019 - Springer
Translin, a highly conserved, DNA/RNA binding protein, is abundantly expressed in brain,
testis and in certain malignancies. It was discovered initially in the quest to find proteins that …

Structural basis for single-stranded RNA recognition and cleavage by C3PO

J Zhang, H Liu, Q Yao, X Yu, Y Chen, R Cui… - Nucleic Acids …, 2016 - academic.oup.com
Translin and translin-associated factor-x are highly conserved in eukaroytes; they can form
heteromeric complexes (known as C3POs) and participate in various nucleic acid …

Structural insights into Drosophila-C3PO complex assembly and 'Dynamic Side Port' model in substrate entry and release

X Mo, X Yang, YA Yuan - Nucleic Acids Research, 2018 - academic.oup.com
In Drosophila and human, component 3 promoter of RISC (C3PO), a heteromeric complex,
enhances RISC assembly and promotes RISC activity. Here, we report crystal structure of …

Selection of RNA aptamers and their recognition of amyloid assemblies

RA Mahood - 2015 - etheses.whiterose.ac.uk
Amyloidoses are a group of protein misfolding disorders which are characterised by the
abnormal accumulation of highly ordered filamentous assemblies, known as amyloid fibrils …