Mitochondrial electron transport chain, ROS generation and uncoupling
RZ Zhao, S Jiang, L Zhang… - … journal of molecular …, 2019 - spandidos-publications.com
The mammalian mitochondrial electron transport chain (ETC) includes complexes I‑IV, as
well as the electron transporters ubiquinone and cytochrome c. There are two electron …
well as the electron transporters ubiquinone and cytochrome c. There are two electron …
The significance of mitochondrial dysfunction in cancer
As an essential organelle in nucleated eukaryotic cells, mitochondria play a central role in
energy metabolism, maintenance of redox balance, and regulation of apoptosis …
energy metabolism, maintenance of redox balance, and regulation of apoptosis …
Modulating ROS to overcome multidrug resistance in cancer
The successful treatment of cancer has significantly improved as a result of targeted therapy
and immunotherapy. However, during chemotherapy, cancer cells evolve and can acquire …
and immunotherapy. However, during chemotherapy, cancer cells evolve and can acquire …
Mitochondrial uncoupling: a key controller of biological processes in physiology and diseases
S Demine, P Renard, T Arnould - Cells, 2019 - mdpi.com
Mitochondrial uncoupling can be defined as a dissociation between mitochondrial
membrane potential generation and its use for mitochondria-dependent ATP synthesis …
membrane potential generation and its use for mitochondria-dependent ATP synthesis …
Mitochondrial disorders of the OXPHOS system
E Fernandez‐Vizarra, M Zeviani - FEBS letters, 2021 - Wiley Online Library
Mitochondrial disorders are among the most frequent inborn errors of metabolism, their
primary cause being the dysfunction of the oxidative phosphorylation system (OXPHOS) …
primary cause being the dysfunction of the oxidative phosphorylation system (OXPHOS) …
Raman spectroscopy in cell biology and microbiology
G Pezzotti - Journal of Raman Spectroscopy, 2021 - Wiley Online Library
The Raman spectrum of living cells and microorganisms contains highly specific fingerprint‐
like signatures, useful in unequivocally identifying different species and interpreting …
like signatures, useful in unequivocally identifying different species and interpreting …
Mitochondrial dysfunction and biogenesis in neurodegenerative diseases: pathogenesis and treatment
Neurodegenerative diseases are a heterogeneous group of disorders that are incurable and
characterized by the progressive degeneration of the function and structure of the central …
characterized by the progressive degeneration of the function and structure of the central …
Mitochondrial structure and bioenergetics in normal and disease conditions
M Protasoni, M Zeviani - International journal of molecular sciences, 2021 - mdpi.com
Mitochondria are ubiquitous intracellular organelles found in almost all eukaryotes and
involved in various aspects of cellular life, with a primary role in energy production. The …
involved in various aspects of cellular life, with a primary role in energy production. The …
From OCR and ECAR to energy: Perspectives on the design and interpretation of bioenergetics studies
Biological energy transduction underlies all physiological phenomena in cells. The
metabolic systems that support energy transduction have been of great interest due to their …
metabolic systems that support energy transduction have been of great interest due to their …
Hypoxic pulmonary vasoconstriction: from molecular mechanisms to medicine
Hypoxic pulmonary vasoconstriction (HPV) is a homeostatic mechanism that is intrinsic to
the pulmonary vasculature. Intrapulmonary arteries constrict in response to alveolar hypoxia …
the pulmonary vasculature. Intrapulmonary arteries constrict in response to alveolar hypoxia …