[HTML][HTML] Influence of genetic polymorphism towards pulmonary tuberculosis susceptibility

M Harishankar, P Selvaraj, R Bethunaickan - Frontiers in medicine, 2018 - frontiersin.org
Tuberculosis (TB) is still remains the major threat for human health worldwide. Several case-
control, candidate-gene, family studies and genome-wide association studies (GWAS) …

[HTML][HTML] Vitamin D receptor ApaI (rs7975232), BsmI (rs1544410), Fok1 (rs2228570), and TaqI (rs731236) gene polymorphisms and susceptibility to pulmonary …

A Mohammadi, H Khanbabaei… - Journal of Microbiology …, 2020 - Elsevier
Polymorphisms of vitamin D receptors (VDRs), ApaI, BsmI, FokI, and TaqI might affect
susceptibility to tuberculosis (TB). In this systematic review and meta-analysis, all published …

Natural killer cells are recruited during pulmonary tuberculosis and their ex vivo responses to mycobacteria vary between healthy human donors in association with …

D Portevin, LE Via, S Eum, D Young - Cellular microbiology, 2012 - Wiley Online Library
Humans vary widely in their susceptibility to tuberculosis. While only a minority will progress
to disease, the majority of healthy individuals exposed to M ycobacterium tuberculosis …

The role of host genetics (and genomics) in tuberculosis

V Naranbhai - Microbiology Spectrum, 2016 - Am Soc Microbiol
Familial risk of tuberculosis (TB) has been recognized for centuries. Largely through studies
of mono-and dizygotic twin concordance rates, studies of families with Mendelian …

[HTML][HTML] Reproduction, infection and killer-cell immunoglobulin-like receptor haplotype evolution

BS Penman, A Moffett, O Chazara, S Gupta, P Parham - Immunogenetics, 2016 - Springer
Killer-cell immunoglobulin-like receptors (KIRs) are encoded by one of the most polymorphic
families in the human genome. KIRs are expressed on natural killer (NK) cells, which have …

[HTML][HTML] Outdoor air pollution affects tuberculosis development based on geographical information system modeling

E Rajaei, M Hadadi, M Madadi, J Aghajani… - Biomedical and …, 2018 - journals.lww.com
Background: Daily intake of air is 30 Ib as compared with 2-Ib of food and 4½ of water.
Thereby, breathing-contaminated air is as harmful as drinking or eating contaminated water …

Activating KIRs alter susceptibility to pulmonary tuberculosis in a South African population

M Salie, M Daya, M Möller, EG Hoal - Tuberculosis, 2015 - Elsevier
We investigate the role of killer immunoglobulin-like receptor (KIR) genes and human
leukocyte antigen class-I (HLA) variants in susceptibility to tuberculosis in a South African …

Association of KIR3DS1+ HLA-B Bw4Ile80 combination with susceptibility to tuberculosis in Lur population of Iran

F Shahsavar, T Mousavi, A Azargoon… - Iranian Journal of …, 2012 - iji.sums.ac.ir
Background: Natural killer (NK) cells are the effector cells of innate immunity that respond to
infection and tumor. Interactions between killer cell immunoglobulin like receptors (KIR) and …

Killer cell immunoglobulin like receptor gene association with tuberculosis

SS Pydi, SR Sunder, S Venkatasubramanian… - Human Immunology, 2013 - Elsevier
NK cells are vital components of innate immune system and are the first cells which come
into picture mediating resistance against intracellular pathogens. NK cell cytotoxicity is …

The potential role of HLA-G in the pathogenesis of HBV infection: Immunosuppressive or immunoprotective?

S Rashidi, L Farhadi, F Ghasemi… - Infection, Genetics and …, 2020 - Elsevier
The non-classical human leukocyte antigens (HLA)-G could be generally considered as a
potent tolerogenic molecule, which modulates immune responses. HLA-G due to the …