Background Precision medicine, space exploration, drug discovery to characterization of
dark chemical space of habitats and organisms, metabolomics takes a centre stage in …

Progress in mass spectrometry lipidomics has led to a rapid proliferation of studies across
biology and biomedicine. These generate extremely large raw datasets requiring …

Ferroptosis, a non-apoptotic form of cell death marked by iron-dependent lipid peroxidation,
has a key role in organ injury, degenerative disease and vulnerability of therapy-resistant …

The spatiotemporal structure of the human microbiome,, proteome and metabolome, reflects
and determines regional intestinal physiology and may have implications for disease. Yet …

Fatty acid isomers are responsible for an under-reported lipidome diversity across all
kingdoms of life. Isomers of unsaturated fatty acids are often masked in contemporary …

Most microbes evolve faster than their hosts and should therefore drive evolution of host–
microbe interactions. However, relatively little is known about the characteristics that define …

Taurine-respiring gut bacteria produce H2S with ambivalent impact on host health. We
report the isolation and ecophysiological characterization of a taurine-respiring mouse gut …

Ferroptosis is a form of cell death that has received considerable attention not only as a
means to eradicate defined tumour entities but also because it provides unforeseen insights …

Nuclear receptor-binding SET-domain protein 1 (NSD1), a methyltransferase that catalyzes
H3K36me2, is essential for mammalian development and is frequently dysregulated in …

Lipidomics studies suffer from analytical and annotation challenges because of the great
structural similarity of many of the lipid species. To improve lipid characterization and …