Patients with isolated rapid-eye-movement sleep behaviour disorder (RBD) are commonly
regarded as being in the early stages of a progressive neurodegenerative disease involving …

For the last two decades, pathogenic concepts in Parkinson disease (PD) have revolved
around the toxicity and spread of α-synuclein. Thus, α-synuclein would follow caudo-rostral …

The Parkinson's disease (PD) research field has seen the advent of several promising
biomarkers and a deeper understanding of the clinical features of the disease from the …

Background and Objectives Multiple system atrophy (MSA) is a progressive
neurodegenerative disorder caused by the abnormal accumulation of α-synuclein in the …

Since its first description in 1986 by Dr. Carlos Schenck, and his group's subsequent report
of the delayed emergence of a Parkinsonian disorder in idiopathic RBD patients one decade …

REM sleep without atonia (RSWA) is the polysomnographic (PSG) hallmark of rapid eye
movement (REM) sleep behavior disorder (RBD), a feature essential for the diagnosis of this …

This manuscript presents an overview of REM sleep behaviour disorder (RBD) with a
special focus on European contributions. After an introduction examining the history of the …

The present review focuses on REM sleep without atonia (RSWA) scoring methods. In
consideration of the numerous papers published in the last decade, that used different …

Rapid eye movement (REM) sleep behavior disorder (RBD) is characterized by dream
enactment and the loss of muscle atonia during REM sleep, known as REM sleep without …

Sleep disturbances are among the common nonmotor symptoms in patients with Parkinson's
disease (PD). Sleep can be disrupted by nocturnal motor and nonmotor symptoms and other …