The function of the mammalian heart depends on the interplay between different cardiac cell
types. The deployment of these cells, with precise spatiotemporal regulation, is also …

The field of vascular biology has gained enormous insight from the use of Cre and inducible
Cre mouse models to temporally and spatially manipulate gene expression within the …

Muscle regeneration requires the coordinated interaction of multiple cell types. Satellite cells
have been implicated as the primary stem cell responsible for regenerating muscle, yet the …

Tracheal and esophageal disorders are prevalent in humans and difficult to accurately
model in mice. We therefore established a three-dimensional organoid model of esophageal …

Cre/LoxP has broad utility for studying the function, development, and oncogenic
transformation of pancreatic cells in mice. Here we provide an overview of the Cre driver …

Longitudinal bone growth, achieved through endochondral ossification, is accomplished by
a cartilaginous structure, the physis or growth plate, comprised of morphologically distinct …

In the mouse, one of the earliest events in the determination of cell fate is the segregation of
cells into germ layers during gastrulation; however, the cellular and molecular details are not …

The metabolic, digestive and homeostatic roles of the liver are dependent on proper
crosstalk and organization of hepatic cell lineages. These hepatic cell lineages are derived …

The transcription factor GATA-2 plays vital roles in quite diverse developmental programs,
including hematopoietic stem cell (HSC) survival and proliferation. We previously identified …

Wound‐induced hair follicle neogenesis (WIHN) has been an important model to study hair
follicle regeneration during wound repair. However, the cellular and molecular components …