Reward contributions to serotonergic functions

Z Liu, R Lin, M Luo - Annual review of neuroscience, 2020 - annualreviews.org
The brain serotonin systems participate in numerous aspects of reward processing, although
it remains elusive how exactly serotonin signals regulate neural computation and reward …

Current limitations and candidate potential of 5-HT7 receptor antagonism in psychiatric pharmacotherapy

R Okubo, T Hasegawa, K Fukuyama… - Frontiers in …, 2021 - frontiersin.org
Several mood-stabilizing atypical antipsychotics and antidepressants weakly block
serotonin (5-HT) receptor type-7 (5-HT7R); however, the contributions of 5-HT7R …

Modulating role of serotonergic signaling in sleep and memory

S Vaseghi, S Arjmandi-Rad, M Eskandari… - Pharmacological …, 2022 - Springer
Serotonin is an important neurotransmitter with various receptors and wide-range effects on
physiological processes and cognitive functions including sleep, learning, and memory. In …

Ginsenoside Rg3 modulates spatial memory and fear memory extinction by the HPA axis and BDNF-TrkB pathway in a rat post-traumatic stress disorder

B Sur, B Lee - Journal of Natural Medicines, 2022 - Springer
Post-traumatic stress disorder (PTSD) is a serious mental disorder that can develop after
exposure to extreme stress. Korean red ginseng, whose major active component is …

Impact of specific serotonin receptor modulation on restricted repetitive behaviors

BD Alvarez, C Cavazos, CA Morales… - Frontiers in behavioral …, 2022 - frontiersin.org
Restricted, repetitive behaviors (RRBs) are commonly divided into two behavioral
categories, lower-order and higher-order RRBs. Individuals displaying lower-order motoric …

Modulation of the serotonergic receptosome in the treatment of anxiety and depression: a narrative review of the experimental evidence

GR Villas-Boas, SN Lavorato, MM Paes… - Pharmaceuticals, 2021 - mdpi.com
Serotonin (5-HT) receptors are found throughout central and peripheral nervous systems,
mainly in brain regions involved in the neurobiology of anxiety and depression. 5-HT …

Myricetin Inhibited Fear and Anxiety‐Like Behaviors by HPA Axis Regulation and Activation of the BDNF‐ERK Signaling Pathway in Posttraumatic Stress Disorder …

B Sur, B Lee - Evidence‐Based Complementary and …, 2022 - Wiley Online Library
Posttraumatic stress disorder (PTSD) is a stress‐related psychiatric or mental disorder
characterized by experiencing a traumatic stress. The cause of such PTSD is dysregulation …

Serotonin modulation of hippocampal functions: From anatomy to neurotherapeutics

C Bombardi, A Grandis, N Pivac, M Sagud… - Progress in brain …, 2021 - Elsevier
The hippocampal region receives a dense serotoninergic innervation originating from both
medial and dorsal raphe nuclei. This innervation regulates hippocampal activity through the …

Participation of Hippocampal 5-HT5A, 5-HT6 and 5-HT7 Serotonin Receptors on the Consolidation of Social Recognition Memory

SD Schmidt, CG Zinn, LE Cavalcante, FF Ferreira… - Neuroscience, 2022 - Elsevier
Social recognition is the ability of animals to identify and recognize a conspecific. The
consolidation of social stimuli in long-term memory is crucial for the establishment and …

The 5-HT2A, 5-HT5A, and 5-HT6 serotonergic receptors in the medial prefrontal cortex behave differently in extinction learning: Does social support play a role?

CP Farias, AKO Leite, BE Schmidt… - Behavioural Brain …, 2024 - Elsevier
Studies on the social modulation of fear have revealed that in social species, individuals in a
distressed state show better recovery from aversive experiences when accompanied …