The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …

Simple Summary Tumor immune microenvironment is an important structural component of
malignant pleural mesothelioma that contributes to disease growth support and progression …

Disclosures: Dr. Badhai reported a patent to 19209921.8-1112 pending. Dr. Monkhorst
reported personal fees from Roche, personal fees from Pfizer, personal fees from BMS …

In this study, we engineered mesenchymal stem cells (MSCs) to over-express basic
fibroblast growth factor (bFGF) and evaluated its effects on fracture healing. Adipose-derived …

Canine malignant mesothelioma (cMM) is a rare and drug-resistant malignant tumor. Due to
few patients and experimental models, there have not been enough studies to demonstrate …

The FGFR1 is a therapeutic target under investigation in multiple solid tumors and clinical
trials of selective tyrosine kinase inhibitors (TKI) are underway. Treatment with a single TKI …

Rationale: Malignant pleural mesothelioma is an aggressive malignancy characterized by
frequent resistance to chemo-and radiotherapy, poor outcome, and limited therapeutic …

Severe uterine injury is a major cause of endometrial scar formation and female infertility. At
present, the methods for accelerating injured uterine healing are still lacking. Genetic …

Purpose: Despite intense research, treatment options for patients with mesothelioma are
limited and offer only modest survival advantage. We screened a large panel of compounds …

Malignant pleural mesothelioma (MPM) is an aggressive malignancy with very limited
therapeutic options. Fibroblast growth factor (FGF) signals play important roles in …