The RNA-binding protein human antigen R (HuR) is a well-established regulator of gene
expression at the posttranscriptional level. Its dysregulation has been implicated in various …

Introduction In fragment-based drug design, fragment linking is a popular strategy where two
fragments binding to different sub-pockets of a target are linked together. This attractive …

In recent years, RNA has gained traction both as a therapeutic molecule and as a
therapeutic target in several human pathologies. In this review, we consider the approach of …

In recent years, advances in biomedicine have revealed an important role for post-
transcriptional mechanisms of gene expression regulation in pathologic conditions. In …

The RNA-binding protein human antigen R (HuR) regulates stability, translation, and
nucleus-to-cytoplasm shuttling of its target mRNAs. This protein has been progressively …

Cancer is a disease that poses a serious threat to human health, the occurrence and
development of which involves complex molecular mechanisms. Long non-coding RNAs …

Cardiac fibrosis can be mitigated by limiting fibroblast-to-myofibroblast differentiation and
proliferation. Human antigen R (HuR) modulates messenger RNA stability and expression of …

Human antigen R (HuR), which is a mRNA‐binding protein that stabilizes and regulates
mRNA translation, is found to have increased expression in inflammation, cancer and other …

RNA-binding proteins (RBPs) play critical roles in regulating post-transcriptional gene
expression, managing processes such as mRNA splicing, stability, and translation. In normal …

RNA-binding proteins (RBPs) refer to a class of proteins that participate in alternative
splicing, RNA stability, polyadenylation, localization and translation of RNAs, thus regulating …