Kaempferol and its derivatives are naturally occurring phytochemicals with promising
bioactivities. This flavonol can reduce the lipid oxidation in the human body, prevent the …

Todays, nano-pharmaceutics is emerging as an important field of science to develop and
improve efficacy of different drugs. Although nutraceuticals are currently being utilized in the …

Epigenetic factors are critical regulators of biological and pathological mechanisms and they
could interact with different molecular pathways. Targeting epigenetic factors has been an …

Cost-efficacy of currently applied treatments is an issue in overall cancer management
challenging healthcare and causing tremendous economic burden to societies around the …

Reactive oxygen species (ROS) are noxious to cells because their increased level interacts
with the body's defense mechanism. These species also cause mutations and uncontrolled …

The nuclear factor erythroid 2-related factor 2 (Nrf2) is a master regulator of redox balance
and it responds to various cell stresses that oxidative stress is the most well-known one. The …

With the advances in biomedical technologies, natural products have attracted substantial
public attention in the area of drug discovery. Flavonoids are a class of active natural …

Background Kaempferol is extracted from Hedyotis diffusa, exerting an obvious anti-cancer
effect. Here in the present study, we explored the anti-cancer effects and mechanism of …

Breast cancer (BC) is one of the most common cancers in females and is responsible for the
highest cancer-related deaths following lung cancer. The complex tumor microenvironment …

Type II diabetes mellitus and its related complications are growing public health problems.
Many natural products present in our diet, including polyphenols, can be used in treating …