Experimental binding energies in supramolecular complexes
F Biedermann, HJ Schneider - Chemical reviews, 2016 - ACS Publications
On the basis of many literature measurements, a critical overview is given on essential
noncovalent interactions in synthetic supramolecular complexes, accompanied by analyses …
noncovalent interactions in synthetic supramolecular complexes, accompanied by analyses …
Androgen receptor: structure, role in prostate cancer and drug discovery
Androgens and androgen receptors (AR) play a pivotal role in expression of the male
phenotype. Several diseases, such as androgen insensitivity syndrome (AIS) and prostate …
phenotype. Several diseases, such as androgen insensitivity syndrome (AIS) and prostate …
Principles and applications of halogen bonding in medicinal chemistry and chemical biology
Halogen bonding has been known in material science for decades, but until recently,
halogen bonds in protein–ligand interactions were largely the result of serendipitous …
halogen bonds in protein–ligand interactions were largely the result of serendipitous …
Thyroid hormone transporters
S Groeneweg, FS van Geest, RP Peeters… - Endocrine …, 2020 - academic.oup.com
Thyroid hormone transporters at the plasma membrane govern intracellular bioavailability of
thyroid hormone. Monocarboxylate transporter (MCT) 8 and MCT10, organic anion …
thyroid hormone. Monocarboxylate transporter (MCT) 8 and MCT10, organic anion …
Halogen bonding (X‐bonding): A biological perspective
MR Scholfield, CMV Zanden, M Carter… - Protein Science, 2013 - Wiley Online Library
The concept of the halogen bond (or X‐bond) has become recognized as contributing
significantly to the specificity in recognition of a large class of halogenated compounds. The …
significantly to the specificity in recognition of a large class of halogenated compounds. The …
Chemistry and biology in the biosynthesis and action of thyroid hormones
S Mondal, K Raja, U Schweizer… - Angewandte Chemie …, 2016 - Wiley Online Library
Thyroid hormones (THs) are secreted by the thyroid gland. They control lipid, carbohydrate,
and protein metabolism, heart rate, neural development, as well as cardiovascular, renal …
and protein metabolism, heart rate, neural development, as well as cardiovascular, renal …
[HTML][HTML] Circadian rhythm transcription factor CLOCK regulates the transcriptional activity of the glucocorticoid receptor by acetylating its hinge region lysine cluster …
N Nader, GP Chrousos, T Kino - The FASEB Journal, 2009 - ncbi.nlm.nih.gov
Glucocorticoids, end products of the hypothalamic-pituitary-adrenal axis, influence functions
of virtually all organs and tissues through the glucocorticoid receptor (GR). Circulating levels …
of virtually all organs and tissues through the glucocorticoid receptor (GR). Circulating levels …
Thyroid hormone receptor localization in target tissues
CS Anyetei-Anum, VR Roggero… - Journal of …, 2018 - joe.bioscientifica.com
The thyroid hormone receptors, TRα1, TRβ1 and other subtypes, are members of the
nuclear receptor superfamily that mediate the action of thyroid hormone signaling in …
nuclear receptor superfamily that mediate the action of thyroid hormone signaling in …
The race to bash NASH: emerging targets and drug development in a complex liver disease
FA Romero, CT Jones, Y Xu, M Fenaux… - Journal of medicinal …, 2020 - ACS Publications
Nonalcoholic steatohepatitis (NASH) is a severe form of nonalcoholic fatty liver disease
(NAFLD) characterized by liver steatosis, inflammation, and hepatocellular damage. NASH …
(NAFLD) characterized by liver steatosis, inflammation, and hepatocellular damage. NASH …
Genomic and non-genomic mechanisms of action of thyroid hormones and their catabolite 3, 5-diiodo-l-thyronine in mammals
M Giammanco, CM Di Liegro, G Schiera… - International Journal of …, 2020 - mdpi.com
Since the realization that the cellular homologs of a gene found in the retrovirus that
contributes to erythroblastosis in birds (v-erbA), ie the proto-oncogene c-erbA encodes the …
contributes to erythroblastosis in birds (v-erbA), ie the proto-oncogene c-erbA encodes the …