Fluorescent proteins have revolutionized biomedical research as they are easy to use for
protein tagging, cope without fixation or permeabilization, and thus, enable live cell imaging …

Sugarcane is the source of 80% of the sugar and 26% of the bioethanol produced globally.
However, its complex, highly polyploid genome (2 n= 100–120) impedes crop improvement …

The CRISPR/Cas9 system has recently been shown to facilitate high levels of precise
genome editing using adeno-associated viral (AAV) vectors to serve as donor template DNA …

The inheritance of variants that lead to coding changes in, or the mis-expression of, genes
critical to pancreatic beta cell function can lead to alterations in insulin secretion and …

Although current stem cell therapies exhibit promising potential, the extended process of
employing autologous cells and the necessity for donor–host matching to avert the rejection …

Genetic pest control strategies based on precise sex separation and only releasing sterile
males can be accomplished by site-specific genome editing. In the current study, we showed …

Background/Aims: CRISPR-Cas9, a RNA-guided targeted genome editing tool, has
revolutionized genetic engineering by offering the ability to precisely modify DNA. GPRC5B …

Abstract Diabetes, type 1 and type 2 (T1D and T2D), are diseases of epidemic proportions,
which are complicated and defined by genetics, epigenetics, environment, and lifestyle …

Objective: Recessive dystrophic epidermolysis bullosa (RDEB) is a genetic skin fragility and
ultimately lethal blistering disease caused by mutations in the COL7A1 gene which is …

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Introduction: Measurement of pancreatic beta cell mass in animal models is a common …