Pyrroloquinolines, imidazoquinolines, and pyrroloquinazolines with a bridgehead nitrogen

F Dumitrascu, F Georgescu, E Georgescu… - Advances in Heterocyclic …, 2019 - Elsevier
This chapter presents recent advances in the chemistry of heterocyclic ring systems with a
nitrogen bridgehead including pyrrolo [1, 2-a] quinoline, imidazo [1, 2-a] quinoline, imidazo …

Synthesis and Cytotoxic Activity of the Derivatives of N-(Purin-6-yl)aminopolymethylene Carboxylic Acids and Related Compounds

VP Krasnov, OA Vozdvizhenskaya, MA Baryshnikova… - Molecules, 2023 - mdpi.com
Testing a number of N-[omega-(purin-6-yl) aminoalkanoyl] derivatives of 7, 8-difluoro-3, 4-
dihydro-3-methyl-2 H-[1, 4] benzoxazine in a panel of nine tumor cell lines has shown that …

Synthesis of triazole-linked SAM-Adenosine conjugates: functionalization of adenosine at N-1 or N-6 position without protecting groups

C Atdjian, D Coelho, L Iannazzo, M Ethève-Quelquejeu… - Molecules, 2020 - mdpi.com
More than 150 RNA chemical modifications have been identified to date. Among them,
methylation of adenosine at the N-6 position (m6A) is crucial for RNA metabolism, stability …

Palladium-catalyzed intramolecular C–N coupling: Facile synthesis of tetracyclic C (3)-aminoisoindolinones

H Surya Prakash Rao, J Prabhakaran - Synthetic Communications, 2022 - Taylor & Francis
Herein, we report a new methodology to access tetracyclic heterocyclic compounds
incorporating fused isoindolinone and benzimidazoline or isoindolinone and quinazoline …

Ethyl 2-(12-Oxo-10, 12-dihydroisoindolo [1, 2-b] Quinazolin-10-yl) Acetate

V Morlacci, M Aschi, M Chiarini, A Massa, A Arcadi… - Molbank, 2023 - mdpi.com
The title compound has been synthetized using a one-pot cascade process of ethyl (E)-3-(2-
aminophenyl) acrylate and 2-formylbenzonitrile in the presence of Cs2CO3 as the catalyst …