Enhancing Fractionated Cancer Therapy: A Triple-Anthracene Photosensitizer Unleashes Long-Persistent Photodynamic and Luminous Efficacy

Y Wang, H Shen, Z Li, S Liao, B Yin… - Journal of the …, 2024 - ACS Publications
Conventional photodynamic therapy (PDT) is often limited in treating solid tumors due to
hypoxic conditions that impede the generation of reactive oxygen species (ROS), which are …

Tailoring drug delivery systems by microfluidics for tumor therapy

Q Zhang, G Kuang, L Wang, L Fan, Y Zhao - Materials Today, 2024 - Elsevier
Drug delivery systems (DDSs) for tumor treatment is a specialized method aimed at
transporting therapeutic substances, especially anticancer drugs, to specific target areas in …

Recent advances in mitochondria‐targeting theranostic agents

K Qian, S Gao, Z Jiang, Q Ding, Z Cheng - Exploration, 2024 - Wiley Online Library
For its vital role in maintaining cellular activity and survival, mitochondrion is highly involved
in various diseases, and several strategies to target mitochondria have been developed for …

Nature-inspired photocatalytic azo bond cleavage with red light

Z Zhao, J Li, W Yuan, D Cheng, S Ma… - Journal of the …, 2023 - ACS Publications
The emerging field of photoredox catalysis in mammalian cells enables spatiotemporal
regulation of a wealth of biological processes. However, the selective cleavage of stable …

A fluorescent prodrug to fight drug-resistant lung cancer cells via autophagy-driven ferroptosis

F Chen, X Wang, W Chen, C Shao, Y Qian - Sensors and Actuators B …, 2024 - Elsevier
Lung cancer is the second most common malignant tumor worldwide. The problem of drug
resistance in lung cancer leads to treatment failure and recurrence in more than 90% of …

NIR-II-/Tumor Acidity-Triggered Nanoplatform for Precise Chemodynamic/Photodynamic/Hypoxia-Activated Chemo Trimodal Synergistic Therapy

BQ Chen, Y Zhao, YJ Pan, DG Zhang, H Liu… - ACS Materials …, 2023 - ACS Publications
Engineering stimuli-responsive nanoplatforms for multimodal therapeutics to combat the
diversity, complexity, and heterogeneity of malignant tumors has emerged as a new …

Piezoelectric Catalysis Induces Tumor Cell Senescence to Boost Chemo‐Immunotherapy

Z Hao, S Guo, W Tu, Q Wang, J Wang, X Zhang, Y He… - Small, 2024 - Wiley Online Library
Cellular senescence, a vulnerable state of growth arrest, has been regarded as a potential
strategy to weaken the resistance of tumor cells, leading to dramatic improvements in …

A 700 nm LED light activated Ru (II) complex destroys tumor cytoskeleton via photosensitization and photocatalysis

A Dao, S Chen, L Pan, Q Ren, X Wang… - Advanced …, 2024 - Wiley Online Library
Photoactivable chemotherapy (PACT) using metallic complexes provides spatiotemporal
selectivity over drug activation for targeted anticancer therapy. However, the poor absorption …

Photoactivatable Ruthenium Complexes Containing Minimal Straining Benzothiazolyl-1, 2, 3-triazole Chelators for Cancer Treatment

FJ Ballester, A Hernández-García… - Inorganic …, 2024 - ACS Publications
Ruthenium (II) complexes containing diimine ligands have contributed to the development of
agents for photoactivated chemotherapy. Several approaches have been used to obtain …

Peroxynitrite-Free Nitric Oxide-Embedded Nanoparticles Maintain Nitric Oxide Homeostasis for Effective Revascularization of Myocardial Infarcts

J Zhang, S Wang, Q Sun, J Zhang, X Shi, M Yao… - ACS …, 2024 - ACS Publications
Revascularization is crucial for treating myocardial infarction (MI). Nitric oxide (NO), at an
appropriate concentration, is recognized as an ideal and potent pro-angiogenic factor …