The neuropathological hallmarks of Alzheimer disease (AD) include “positive” lesions such
as amyloid plaques and cerebral amyloid angiopathy, neurofibrillary tangles, and glial …

Nerve growth factor (NGF) is a wellcharacterized protein that exerts pharmacological effects
on a group of cholinergic neurons known to atrophy in Alzheimer's disease (AD) …

The number and topographic distribution of immunocytochemically stained parvalbumin
interneurons was determined in the hippocampal formation of control and Alzheimer's …

Hippocampal atrophy and neuron loss are commonly found in Alzheimer's disease (AD).
However, the underlying molecular mechanisms and the fate in the AD hippocampus of …

Alzheimer disease is one of the most challenging demons in our society due to its very high
prevalence and its clinical manifestations which cause deterioration of cognition …

The amyloid precursor protein (APP) modulates synaptic activity, resulting from the fine
tuning of excitatory and inhibitory neurotransmission. GABAergic inhibitory …

This book summarizes the recent advances in the knowledge of the structure and
physiological functions of the calcium-binding proteins in the central nervous system …

The distribution of the calcium-binding protein calretinin was investigated by
immunohistochemistry in the hippocampus, the subicular areas, and the entorhinal cortex in …

Hypoxic-ischemic encephalopathy (HIE) in neonates causes mortality and neurologic
morbidity, including poor cognition with a complex neuropathology. Injury to the cholinergic …

Background Previously, we demonstrated decreased expression of somatostatin mRNA in
aged macaque brain, particularly in the prefrontal cortex. To investigate whether or not this …