Clinical metagenomic next-generation sequencing for pathogen detection

W Gu, S Miller, CY Chiu - Annual Review of Pathology …, 2019 - annualreviews.org
Nearly all infectious agents contain DNA or RNA genomes, making sequencing an attractive
approach for pathogen detection. The cost of high-throughput or next-generation …

The third international consensus guidelines on the management of cytomegalovirus in solid-organ transplantation

CN Kotton, D Kumar, AM Caliendo, S Huprikar… - …, 2018 - journals.lww.com
Despite recent advances, cytomegalovirus (CMV) infections remain one of the most common
complications affecting solid organ transplant recipients, conveying higher risks of …

Cytomegalovirus in solid organ transplant recipients—Guidelines of the American Society of Transplantation Infectious Diseases Community of Practice

RR Razonable, A Humar - Clinical transplantation, 2019 - Wiley Online Library
Cytomegalovirus (CMV) is one of the most common opportunistic infections that affect the
outcome of solid organ transplantation. This updated guideline from the American Society of …

Definitions of resistant and refractory cytomegalovirus infection and disease in transplant recipients for use in clinical trials

RF Chemaly, S Chou, H Einsele… - Clinical Infectious …, 2019 - academic.oup.com
Despite advances in preventive strategies, cytomegalovirus (CMV) infection remains a major
complication in solid organ and hematopoietic cell transplant recipients. CMV infection may …

Progress and challenges in the prevention, diagnosis, and management of cytomegalovirus infection in transplantation

AP Limaye, TM Babu, M Boeckh - Clinical Microbiology Reviews, 2020 - Am Soc Microbiol
Hosts with compromised or naive immune systems, such as individuals living with HIV/AIDS,
transplant recipients, and fetuses, are at the highest risk for complications from …

Next-generation sequencing in clinical microbiology: are we there yet?

SL Mitchell, PJ Simner - Clinics in laboratory medicine, 2019 - labmed.theclinics.com
Next-generation sequencing (NGS) is a method that allows for high-throughput, massively
parallel sequencing of thousands to billions of DNA fragments independently and …

[HTML][HTML] Next-generation sequencing for infectious disease diagnosis and management: a report of the Association for Molecular Pathology

MI Lefterova, CJ Suarez, N Banaei… - The Journal of Molecular …, 2015 - Elsevier
Next-generation sequencing (NGS) technologies are increasingly being used for diagnosis
and monitoring of infectious diseases. Herein, we review the application of NGS in clinical …

Advances in the genotypic diagnosis of cytomegalovirus antiviral drug resistance

S Chou - Antiviral research, 2020 - Elsevier
Cytomegalovirus (CMV) drug resistance mutation maps are updated with recent information
for polymerase inhibitors, the terminase inhibitor letermovir and the UL97 kinase inhibitor …

Antiviral resistance in herpes simplex virus and varicella-zoster virus infections: diagnosis and management

J Piret, G Boivin - Current opinion in infectious diseases, 2016 - journals.lww.com
Antiviral resistance in herpes simplex virus and varicella-z... : Current Opinion in Infectious
Diseases Antiviral resistance in herpes simplex virus and varicella-zoster virus infections …

Exploring multidrug-resistant Klebsiella pneumoniae antimicrobial resistance mechanisms through whole genome sequencing analysis

J Yang, K Zhang, C Ding, S Wang, W Wu, X Liu - BMC microbiology, 2023 - Springer
Abstract Background Antibiotic-resistant Klebsiella pneumoniae has emerged as a critical
public health threat worldwide. Understanding the antimicrobial resistance mechanisms of …