The role of Caenorhabditis elegans in the discovery of natural products for healthy aging

B Kirchweger, J Zwirchmayr, U Grienke… - Natural Product …, 2023 - pubs.rsc.org
Covering: 2012 to 2023 The human population is aging. Thus, the greatest risk factor for
numerous diseases, such as diabetes, cancer and neurodegenerative disorders, is …

Engineering is evolution: a perspective on design processes to engineer biology

SD Castle, M Stock, TE Gorochowski - Nature Communications, 2024 - nature.com
Careful consideration of how we approach design is crucial to all areas of biotechnology.
However, choosing or developing an effective design methodology is not always easy as …

Sexual dimorphic interplays between gut microbiota and antihypertensive drugs

P Bardhan, T Yang - Current Hypertension Reports, 2023 - Springer
Abstract Purpose of the Review The purpose of this study is to review the current literature
regarding gut microbiota in blood pressure regulation and its interactions with …

Engineering bacterial warriors: harnessing microbes to modulate animal physiology

B Gao, D Ruiz, H Case, RE Jinkerson, Q Sun - Current Opinion in …, 2024 - Elsevier
Highlights•Bacteria can modulate the physiology of multicellular organisms including
animals.•Engineered bacteria program model animal Caenorhabditis elegans' physiology.• …

Metabolic model predictions enable targeted microbiome manipulation through precision prebiotics

G Marinos, IK Hamerich, R Debray, N Obeng… - Microbiology …, 2024 - Am Soc Microbiol
While numerous health-beneficial interactions between host and microbiota have been
identified, there is still a lack of targeted approaches for modulating these interactions. Thus …

[HTML][HTML] Caenorhabditis elegans endorse bacterial nanocellulose fibers as functional dietary Fiber reducing lipid markers

A Muñoz-Juan, A Assié, A Esteve-Codina, M Gut… - Carbohydrate …, 2024 - Elsevier
Bacterial nanocellulose (BNC) is a promising dietary fiber with potential as a functional food
additive. We evaluated BNC fibers (BNCf) in the Caenorhabditis elegans model to obtain …

Microbiome composition and function within the Kellet's whelk perivitelline fluid

BN Daniels, J Nurge, C De Smet, O Sleeper… - Microbiology …, 2024 - Am Soc Microbiol
Microbiomes have gained significant attention in ecological research, owing to their diverse
interactions and essential roles within different organismal ecosystems. Microorganisms …

Quantification of Gut Microbiome Metabolites Using Chemical isotope derivatization Strategy combined with LC-MS/MS: Application in Neonatal Hypoxic-Ischemic …

F Xia, P Cui, L Liu, J Chen, Q Zhou, Q Wang… - … of Pharmaceutical and …, 2024 - Elsevier
The gut microbiome plays pivotal roles in various physiological and pathological processes,
with key metabolites including short chain fatty acids (SCFAs), bile acids (BAs), and …

Investigating the Role of Host Genetic Factors and the Microbiome on Microsporidia Infection in C. elegans.

H Tamim El Jarkass - 2023 - tspace.library.utoronto.ca
Microsporidia are a group of poorly understood, obligate intracellular eukaryotic pathogens
with highly reduced genomes. They are currently a major threat to the agricultural industry …

Investigating the Role of Host Genetic Factors and the Microbiome on Microsporidia Infection in C. elegans

HT El Jarkass - 2023 - search.proquest.com
Microsporidia are a group of poorly understood, obligate intracellular eukaryotic pathogens
with highly reduced genomes. They are currently a major threat to the agricultural industry …