Is oxytocin “nature's medicine”?

CS Carter, WM Kenkel, EL MacLean, SR Wilson… - Pharmacological …, 2020 - ASPET
Oxytocin is a pleiotropic, peptide hormone with broad implications for general health,
adaptation, development, reproduction, and social behavior. Endogenous oxytocin and …

The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

[HTML][HTML] Oxytocin receptor is not required for social attachment in prairie voles

KM Berendzen, R Sharma, MA Mandujano, Y Wei… - Neuron, 2023 - cell.com
Prairie voles are among a small group of mammals that display long-term social attachment
between mating partners. Many pharmacological studies show that signaling via the …

[HTML][HTML] Inclusion of females does not increase variability in rodent research studies

AK Beery - Current opinion in behavioral sciences, 2018 - Elsevier
Highlights•Female subjects are underrepresented in animal research.•Recent studies
demonstrate that unstaged female rodents are no more variable than males.•Factorial …

The neural mechanisms and circuitry of the pair bond

H Walum, LJ Young - Nature Reviews Neuroscience, 2018 - nature.com
Love is one of our most powerful emotions, inspiring some of the greatest art, literature and
conquests of human history. Although aspects of love are surely unique to our species …

[HTML][HTML] Oxytocin pathway gene networks in the human brain

DS Quintana, J Rokicki, D van der Meer… - Nature …, 2019 - nature.com
Oxytocin is a neuropeptide involved in animal and human reproductive and social behavior.
Three oxytocin signaling genes have been frequently implicated in human social behavior …

Vasopressin and oxytocin receptor systems in the brain: sex differences and sex-specific regulation of social behavior

KM Dumais, AH Veenema - Frontiers in neuroendocrinology, 2016 - Elsevier
The neuropeptides vasopressin (VP) and oxytocin (OT) and their receptors in the brain are
involved in the regulation of various social behaviors and have emerged as drug targets for …

Oxytocin pathways and the evolution of human behavior

CS Carter - Annual review of psychology, 2014 - annualreviews.org
This review examines the hypothesis that oxytocin pathways—which include the
neuropeptide oxytocin, the related peptide vasopressin, and their receptors—are at the …

Neural mechanisms of mother–infant bonding and pair bonding: Similarities, differences, and broader implications

M Numan, LJ Young - Hormones and behavior, 2016 - Elsevier
This article is part of a Special Issue “Parental Care”. Mother–infant bonding is a
characteristic of virtually all mammals. The maternal neural system may have provided the …

[HTML][HTML] Stress, social behavior, and resilience: insights from rodents

AK Beery, D Kaufer - Neurobiology of stress, 2015 - Elsevier
The neurobiology of stress and the neurobiology of social behavior are deeply intertwined.
The social environment interacts with stress on almost every front: social interactions can be …