From patterns to patients: Advances in clinical machine learning for cancer diagnosis, prognosis, and treatment
Machine learning (ML) is increasingly used in clinical oncology to diagnose cancers, predict
patient outcomes, and inform treatment planning. Here, we review recent applications of ML …
patient outcomes, and inform treatment planning. Here, we review recent applications of ML …
Deep learning in cancer diagnosis, prognosis and treatment selection
Deep learning is a subdiscipline of artificial intelligence that uses a machine learning
technique called artificial neural networks to extract patterns and make predictions from …
technique called artificial neural networks to extract patterns and make predictions from …
Scaling vision transformers to gigapixel images via hierarchical self-supervised learning
Abstract Vision Transformers (ViTs) and their multi-scale and hierarchical variations have
been successful at capturing image representations but their use has been generally …
been successful at capturing image representations but their use has been generally …
Towards a general-purpose foundation model for computational pathology
Quantitative evaluation of tissue images is crucial for computational pathology (CPath) tasks,
requiring the objective characterization of histopathological entities from whole-slide images …
requiring the objective characterization of histopathological entities from whole-slide images …
Cell type and gene expression deconvolution with BayesPrism enables Bayesian integrative analysis across bulk and single-cell RNA sequencing in oncology
Inferring single-cell compositions and their contributions to global gene expression changes
from bulk RNA sequencing (RNA-seq) datasets is a major challenge in oncology. Here we …
from bulk RNA sequencing (RNA-seq) datasets is a major challenge in oncology. Here we …
Multistain deep learning for prediction of prognosis and therapy response in colorectal cancer
S Foersch, C Glasner, AC Woerl, M Eckstein… - Nature medicine, 2023 - nature.com
Although it has long been known that the immune cell composition has a strong prognostic
and predictive value in colorectal cancer (CRC), scoring systems such as the immunoscore …
and predictive value in colorectal cancer (CRC), scoring systems such as the immunoscore …
Machine learning in drug discovery: a review
This review provides the feasible literature on drug discovery through ML tools and
techniques that are enforced in every phase of drug development to accelerate the research …
techniques that are enforced in every phase of drug development to accelerate the research …
Harnessing multimodal data integration to advance precision oncology
Advances in quantitative biomarker development have accelerated new forms of data-driven
insights for patients with cancer. However, most approaches are limited to a single mode of …
insights for patients with cancer. However, most approaches are limited to a single mode of …
[HTML][HTML] Conserved pan-cancer microenvironment subtypes predict response to immunotherapy
The clinical use of molecular targeted therapy is rapidly evolving but has primarily focused
on genomic alterations. Transcriptomic analysis offers an opportunity to dissect the …
on genomic alterations. Transcriptomic analysis offers an opportunity to dissect the …
Federated learning for predicting histological response to neoadjuvant chemotherapy in triple-negative breast cancer
J Ogier du Terrail, A Leopold, C Joly, C Béguier… - Nature medicine, 2023 - nature.com
Triple-negative breast cancer (TNBC) is a rare cancer, characterized by high metastatic
potential and poor prognosis, and has limited treatment options. The current standard of …
potential and poor prognosis, and has limited treatment options. The current standard of …