The role of Hippo‐YAP/TAZ signaling in brain development

BK Terry, S Kim - Developmental Dynamics, 2022 - Wiley Online Library
In order for our complex nervous system to develop normally, both precise spatial and
temporal regulation of a number of different signaling pathways is critical. During both early …

[HTML][HTML] Enriched environment boosts the post-stroke recovery of neurological function by promoting autophagy

YH Deng, LL Dong, YJ Zhang, XM Zhao… - Neural Regeneration …, 2021 - journals.lww.com
Autophagy is crucial for maintaining cellular homeostasis, and can be activated after
ischemic stroke. It also participates in nerve injury and repair. The purpose of this study was …

[HTML][HTML] YAP inhibits HCMV replication by impairing STING-mediated nuclear transport of the viral genome

JH Lee, M Kwon, WY Lim, CR Yoo, Y Yoon… - PLoS …, 2022 - journals.plos.org
YES-associated protein (YAP), a critical actor of the mammalian Hippo signaling pathway
involved in diverse biological events, has gained increased recognition as a cellular factor …

[HTML][HTML] Premature neural progenitor cell differentiation into astrocytes in retinoic acid-induced spina bifida rat model

M Oria, B Pathak, Z Li, K Bakri, K Gouwens… - Frontiers in Molecular …, 2022 - frontiersin.org
During embryonic spinal cord development, neural progenitor cells (NPCs) generate three
major cell lines: neurons, oligodendrocytes, and astrocytes at precise times and locations …

[HTML][HTML] YAP/TAZ-TEAD activity promotes the malignant transformation of cervical intraepithelial neoplasia through enhancing the characteristics and Warburg effect of …

S Li, X Li, Y Yang, S Wu - Apoptosis, 2024 - Springer
A number of studies have confirmed that Yes-associated protein (YAP)/transcriptional co-
activator with PDZ-binding motif (TAZ)-transcriptional enhanced associate domain (TEAD) …

[HTML][HTML] Hydrogel platform facilitating astrocytic differentiation through cell mechanosensing and YAP-mediated transcription

Z Liu, S Mao, Y Hu, F Liu, X Shao - Materials Today Bio, 2023 - Elsevier
Astrocytes are multifunctional glial cells that are essential for brain functioning. Most existing
methods to induce astrocytes from stem cells are inefficient, requiring couples of weeks …

富集环境增强自噬促进缺血性卒中后神经功能的恢复

YH Deng, LL Dong, YJ Zhang, XM Zhao… - 中国神经再生研究(英文 …, 2021 - sjzsyj.com.cn
自噬对于维持细胞稳态至关重要, 其可在缺血性脑卒中后被激活, 参与神经损伤及恢复.
因而文章涉及观察了富集环境是否可通过影响自噬发挥神经保护作用.(1) …

YAP/TAZ DYSREGULATION CONTRIBUTES TO BRAIN PATHOLOGY IN TUBEROUS SCLEROSIS COMPLEX

B Terry - 2022 - scholarshare.temple.edu
Through mutations in the genes TSC1 and TSC2, the genetic disorder Tuberous Sclerosis
Complex (TSC) causes begin tumors to develop in different organs across the body. Of the …

[图书][B] Effects of the Cerebral Palsy-associated Mutation RhoB (S73F) in Cortical Development

K Rajavong - 2022 - search.proquest.com
Cerebral palsy (CP) as a neurodevelopmental disorder that affects individuals' movement,
posture, and balance and occurs in every 2–3 out of 1,000 live births. Symptoms of CP can …

Regulation of neural stem cells and neural development by MGAT5-mediated N-glycosylation

AR Yale - N-glycosylation Branching and Neural Stem Cell …, 2020 - search.proquest.com
4.1 ABSTRACT N-linked glycans attached to cell surface proteins come in a variety of
different configurations that impact protein folding, trafficking, and function and can thus alter …