The central role of dysregulated kinase activity in the etiology of progressive disorders,
including cancer, has fostered incremental efforts on drug discovery programs over the past …

Pd-catalyzed cross-coupling reactions that form C–N bonds have become useful methods to
synthesize anilines and aniline derivatives, an important class of compounds throughout …

1.1. Brief Historical Overview As expected from the fluorine position on the periodic table of
elements, it possesses some extreme properties, in particular, ultimate electronegativity and …

Over the past three decades, Pd-catalyzed cross-coupling reactions have become a
mainstay of organic synthesis. In particular, catalysts derived from biaryl monophosphines …

An unprecedented protocol for urea synthesis directly from methanol and amine was
accomplished. The reaction is highly atom-economical, producing hydrogen as the sole …

C–N cross-coupling bond formation reactions have become valuable approaches to
synthesizing anilines and their derivatives, known as important chemical compounds …

In the pursuit of clean pharmaceutical production, chemists in medicinal industry require
access to new sustainable methodologies to reduce and even eliminate pollution, which is …

Switchable access to carbamates and ureas has been developed by solvent control
palladium‐catalyzed carbonylation of aromatic amines under an atmosphere of carbon …

A series of monoligated L· PdII (Ar) X complexes (L= dialkyl biaryl phosphine) have been
prepared and studied in an effort to better understand an unusual dearomative …

The diaryl urea is an important fragment/pharmacophore in constructing anticancer
molecules due to its near-perfect binding with certain acceptors. The urea NH moiety is a …