Valvular heart disease: shifting the focus to the myocardium

N Ajmone Marsan, V Delgado, DJ Shah… - European heart …, 2023 - academic.oup.com
Adverse cardiac remodelling is the main determinant of patient prognosis in degenerative
valvular heart disease (VHD). However, to give an indication for valvular intervention …

[HTML][HTML] Characterization of degenerative mitral valve disease: differences between fibroelastic deficiency and Barlow's disease

AL van Wijngaarden, BPT Kruithof, T Vinella… - Journal of …, 2021 - mdpi.com
Degenerative mitral valve disease causing mitral valve prolapse is the most common cause
of primary mitral regurgitation, with two distinct phenotypes generally recognized with some …

Definition, prevalence, and clinical significance of mitral annular disjunction in different patient cohorts: a systematic review

S Bennett, J Tafuro, S Duckett, A Appaji… - …, 2022 - Wiley Online Library
Background Mitral annular disjunction (MAD) is a structural abnormality involving a distinct
separation of the left atrium/mitral valve annulus and myocardium continuum. The literature …

Valvular heart disease and cardiomyopathy: reappraisal of their interplay

N Ajmone Marsan, F Graziani, MC Meucci… - Nature Reviews …, 2024 - nature.com
Cardiomyopathies and valvular heart diseases are typically considered distinct diagnostic
categories with dedicated guidelines for their management. However, the interplay between …

[HTML][HTML] Myxomatous mitral valve disease with mitral valve prolapse and mitral annular disjunction: clinical and functional significance of the coincidence

NC Wunderlich, SY Ho, N Flint, RJ Siegel - Journal of Cardiovascular …, 2021 - mdpi.com
The morphological changes that occur in myxomatous mitral valve disease (MMVD) involve
various components, ultimately leading to the impairment of mitral valve (MV) function. In this …

[HTML][HTML] Arrhythmogenic mitral valve prolapse and sudden cardiac death: an update and current perspectives

V Battaglia, G Santangelo, F Bursi, P Simeoli… - Current Problems in …, 2023 - Elsevier
Mitral valve prolapse (MVP) affects about 2% to 3% of the general population, mostly
women, and is the most common cause of primary chronic mitral regurgitation (MR) in …

Imaging considerations and clinical implications of mitral annular disjunction

CS Drescher, MD Kelsey, GS Yankey… - Circulation …, 2022 - Am Heart Assoc
Mitral annular disjunction is increasingly recognized as an important anatomic feature of
mitral valve disease. The presence of mitral annular disjunction, defined as separation …

Morphology of the mural and commissural atrioventricular junction of the mitral valve

A Krawczyk-Ożóg, J Batko, B Zdzierak, A Dziewierz… - Heart, 2024 - heart.bmj.com
Objective This study investigates mitral annular disjunctions (MAD) in the atrial wall-mitral
annulus-ventricular wall junction along the mural mitral leaflet and commissures. Methods …

[HTML][HTML] Mitral valve prolapse, arrhythmias, and sudden cardiac death: the role of multimodality imaging to detect high-risk features

AG Pavon, P Monney, J Schwitter - Diagnostics, 2021 - mdpi.com
Mitral valve prolapse (MVP) was first described in the 1960s, and it is usually a benign
condition. However, a subtype of patients are known to have a higher incidence of …

[HTML][HTML] Arrhythmic mitral valve prolapse and mitral annular disjunction: clinical features, pathophysiology, risk stratification, and management

AK Chakrabarti, F Bogun, JJ Liang - Journal of Cardiovascular …, 2022 - mdpi.com
Mitral valve prolapse (MVP) is a common cause of valvular heart disease. Although many
patients with MVP have a benign course, there is increasing recognition of an arrhythmic …