Flow cytometry and cell sorting of heterogeneous microbial populations: the importance of single-cell analyses
The most fundamental questions such as whether a cell is alive, in the sense of being able
to divide or to form a colony, may sometimes be very hard to answer, since even axenic …
to divide or to form a colony, may sometimes be very hard to answer, since even axenic …
Optical detection of single molecules
▪ Abstract Recent advances in ultrasensitive instrumentation have allowed for the detection,
identification, and dynamic studies of single molecules in the condensed phase. This …
identification, and dynamic studies of single molecules in the condensed phase. This …
Molecular motors
EY Chan - US Patent 6,210,896, 2001 - Google Patents
The present invention relates to molecular motors and their use in linear analysis of
polymers. In particular, molecular motors are used to move polymers with respect to a station …
polymers. In particular, molecular motors are used to move polymers with respect to a station …
Methods and products for analyzing polymers
EY Chan - US Patent 8,168,380, 2012 - Google Patents
US8168380B2 - Methods and products for analyzing polymers - Google Patents
US8168380B2 - Methods and products for analyzing polymers - Google Patents Methods and …
US8168380B2 - Methods and products for analyzing polymers - Google Patents Methods and …
Data registration and selective single-molecule analysis using multi-parameter fluorescence detection
C Eggeling, S Berger, L Brand, JR Fries… - Journal of …, 2001 - Elsevier
A general strategy to identify and quantify sample molecules in dilute solution employing a
new spectroscopic method for data registration and specific burst analysis denoted as multi …
new spectroscopic method for data registration and specific burst analysis denoted as multi …
Single-molecule fluorescence analysis in solution
RA Keller, WP Ambrose, PM Goodwin, JH Jett… - Applied …, 1996 - opg.optica.org
Over the past five years, several groups have developed the capability to detect and identify
single fluorescent molecules in solution as the molecules flow through a focused laser …
single fluorescent molecules in solution as the molecules flow through a focused laser …
Fluorescence correlations, single molecule detection and large number screening applications in biotechnology
R Rigler - Journal of biotechnology, 1995 - Elsevier
Fluorescence correlation spectroscopy (FCS), when carried out under conditions with low
background as obtained in very small volume elements, is a powerful tool for examining …
background as obtained in very small volume elements, is a powerful tool for examining …
Quantitative identification of different single molecules by selective time-resolved confocal fluorescence spectroscopy
JR Fries, L Brand, C Eggeling, M Köllner… - The Journal of …, 1998 - ACS Publications
Using a confocal epi-illuminated microscope together with a pulsed laser, new applications
of the recently developed, real-time spectroscopic technique BIFL (burst integrated …
of the recently developed, real-time spectroscopic technique BIFL (burst integrated …
Methods of analyzing polymers using ordered label strategies
EY Chan - US Patent 6,403,311, 2002 - Google Patents
The invention relates to methods and products for analyzing polymers. The polymers are
analyzed by reconstructing sequence information from population data sets. The data sets …
analyzed by reconstructing sequence information from population data sets. The data sets …