The landscape of survival analysis is constantly being revolutionized to answer biomedical
challenges, most recently the statistical challenge of censored covariates rather than …

The purpose of this report is to provide guidance on the use of otoacoustic emissions (OAEs)
as a clinical trial outcome measure for pharmaceutical interventions developed to prevent …

We develop a new multiple imputation approach for M-regression models with censored
covariates. Instead of specifying parametric likelihoods, our method imputes the censored …

In cohort studies the outcome is often time to a particular event, and subjects are followed at
regular intervals. Periodic visits may also monitor a secondary irreversible event influencing …

Establishing adequacy of psychometric properties of an instrument involves acquisition and
evaluation of evidence based on item content and internal structure. Content validity …

Content validity elicits expert opinion regarding items of a psychometric instrument. Expert
opinion can be elicited in many forms: for example, how essential an item is or its relevancy …

Developing valid and reliable instruments is crucial, but costly and time-consuming in health
care research and evaluation. The Food and Drug Administration (FDA) and the National …

Survival analysis, born over 360 years ago from the mortality studies of Graunt and Halley,
originally focused on time to death. Since then, it has broadened to include any time to …

The proposal herein is put forth by the University of Kansas Medical Center's Department of
Biostatistics, with the full support of the Biostatistics Faculty and the Department Chair, Dr …