The multirole of liposomes in therapy and prevention of infectious diseases

R Nisini, N Poerio, S Mariotti, F De Santis… - Frontiers in …, 2018 - frontiersin.org
Liposomes are closed bilayer structures spontaneously formed by hydrated phospholipids
that are widely used as efficient delivery systems for drugs or antigens, due to their capability …

Recent advances in inhalable liposomes for treatment of pulmonary diseases: concept to clinical stance

PP Mehta, D Ghoshal, AP Pawar, SS Kadam… - Journal of drug delivery …, 2020 - Elsevier
Liposomes and liposomes-based drug delivery systems are promising carriers in the rapidly
evolving field of nanomedicine. Liposomes are receiving growing attention in the scientific …

Tuberculosis drug discovery: Progression and future interventions in the wake of emerging resistance

S Perveen, D Kumari, K Singh, R Sharma - European Journal of Medicinal …, 2022 - Elsevier
The emergence of drug resistance continues to afflict TB control where drug resistant strains
have become a global health concern. Contrary to drug-sensitive TB, the treatment of …

[HTML][HTML] Challenges for pulmonary delivery of high powder doses

I Sibum, P Hagedoorn, AH de Boer, HW Frijlink… - International journal of …, 2018 - Elsevier
In recent years there is an increasing interest in the pulmonary delivery of large cohesive
powder doses, ie drugs with a low potency such as antibiotics or drugs with a high potency …

Dry powder inhalers of antitubercular drugs

N Nainwal, Y Sharma, V Jakhmola - Tuberculosis, 2022 - Elsevier
Despite advancements in the medical and pharmaceutical fields, tuberculosis remains a
major health problem globally. Patients do not widely accept the conventional approach to …

Engineered drug delivery devices to address Global Health challenges

I Sadeghi, J Byrne, R Shakur, R Langer - Journal of Controlled Release, 2021 - Elsevier
There is a dire need for innovative solutions to address global health needs. Polymeric
systems have been shown to provide substantial benefit to all sectors of healthcare …

Potential of dry powder inhalers for tuberculosis therapy: facts, fidelity and future

P Mehta, C Bothiraja, S Kadam… - … cells, nanomedicine, and …, 2018 - Taylor & Francis
Tuberculosis (TB) is a contagious and airborne infectious disease caused by the pathogen
Mycobacterium tuberculosis (Mtb). In spite of substantial research efforts, continuous …

[HTML][HTML] Design and processing of drug delivery formulations of therapeutic deep eutectic systems for tuberculosis

A Roda, F Santos, AA Matias, A Paiva… - The Journal of …, 2020 - Elsevier
Therapeutic deep eutectic systems (THEDES) emerged as alternative therapeutic agents
that can enhance the bioavailability of the currently used active pharmaceutical ingredients …

In silico evaluation of particle transport and deposition in the airways of individual patients with chronic obstructive pulmonary disease

K Kadota, K Matsumoto, H Uchiyama, S Tobita… - European Journal of …, 2022 - Elsevier
Inhalation therapy can effectively treat chronic obstructive pulmonary disease (COPD), but
the physical factors determining the appropriate aerosol delivery into the targeted airways …

Development of inhalable ATRA-loaded PLGA nanoparticles as host-directed immunotherapy against tuberculosis

AZ Bahlool, S Fattah, A O'Sullivan, B Cavanagh… - Pharmaceutics, 2022 - mdpi.com
Developing new effective treatment strategies to overcome the rise in multi-drug resistant
tuberculosis cases (MDR-TB) represents a global challenge. A host-directed therapy (HDT) …