Lipid-based nanovesicular drug delivery systems

T Limongi, F Susa, M Marini, M Allione, B Torre… - Nanomaterials, 2021 - mdpi.com
In designing a new drug, considering the preferred route of administration, various
requirements must be fulfilled. Active molecules pharmacokinetics should be reliable with a …

Pulmonary delivery of anticancer drugs via lipid-based nanocarriers for the treatment of lung cancer: An update

IM Abdulbaqi, RA Assi, A Yaghmur, Y Darwis… - Pharmaceuticals, 2021 - mdpi.com
Lung cancer (LC) is the leading cause of cancer-related deaths, responsible for
approximately 18.4% of all cancer mortalities in both sexes combined. The use of systemic …

In vitro and in vivo evaluation of the effectiveness and safety of amygdalin as a cancer therapy

FIA El-Ela, A Gamal, HA Elbanna, AH ElBanna… - Pharmaceuticals, 2022 - mdpi.com
Cancer is one of the most important causes of death worldwide. Several studies have shown
the efficacy of apricot kernel seed as a cancer therapy due to the presence of amygdalin …

Improving the antitumor activity and bioavailability of sonidegib for the treatment of skin cancer

A Gamal, H Saeed, FIA El-Ela, HF Salem - Pharmaceutics, 2021 - mdpi.com
Throughout the United States and the world, skin cancer is the most frequent form of cancer.
Sonidegib (SNG) is a hedgehog inhibitor that has been used for skin cancer treatment …

The optimized delivery of triterpenes by liposomal nanoformulations: Overcoming the challenges

A Milan, A Mioc, A Prodea, M Mioc, R Buzatu… - International journal of …, 2022 - mdpi.com
The last decade has witnessed a sustained increase in the research development of modern-
day chemo-therapeutics, especially for those used for high mortality rate pathologies …

Formulation, pharmacokinetics, and antibacterial activity of florfenicol-loaded niosome

SG Abonashey, HAFM Hassan, MA Shalaby… - Drug Delivery and …, 2024 - Springer
The growing interest in employing nano-sized pharmaceutical formulations in veterinary
medicine has prompted the exploration of the novel nanocarriers' ability to augment the …

Enhancing the bioavailability and efficacy of vismodegib for the control of skin cancer: in vitro and in vivo studies

HF Salem, A Gamal, H Saeed, M Kamal, AS Tulbah - Pharmaceuticals, 2022 - mdpi.com
Skin cancer is the most frequent cancer throughout the world. Vismodegib (VSD) is a
hedgehog blocker approved for the prevention and treatment of skin cancer. VSD, however …

[HTML][HTML] Design and characterization of atorvastatin dry powder formulation as a potential lung cancer treatment

AS Tulbah, A Gamal - Saudi Pharmaceutical Journal, 2021 - Elsevier
Lung cancer is the leading cause of cancer death. Many studies have shown the beneficial
effects of Atorvastatin in decreasing the mortality risk and improving survival among patients …

Treatment of Brucellosis in Guinea Pigs via a Combination of Engineered Novel pH-Responsive Curcumin Niosome Hydrogel and Doxycycline-Loaded Chitosan–Sodium Alginate …

FI Abo El-Ela, KH Hussein, HA El-Banna, A Gamal… - AAPS …, 2020 - Springer
Brucellosis is a common zoonotic infection, particularly in the developing world. The
recommended treatment regimens for brucellosis involve the use of two medications such as …

The impact of improving dermal permeation on the efficacy and targeting of liposome nanoparticles as a potential treatment for breast cancer

HF Salem, A Gamal, H Saeed, AS Tulbah - Pharmaceutics, 2021 - mdpi.com
Breast cancer is the most frequent malignancy in women. This work focuses on developing
deformable liposomes as a potential carrier for breast cancer treatment and studying the …