Classic costimulatory interactions in MAIT cell responses: from gene expression to immune regulation
NI Wang, M Ninkov… - Clinical and Experimental …, 2023 - academic.oup.com
Mucosa-associated invariant T (MAIT) cells are evolutionarily conserved, innate-like T
lymphocytes with enormous immunomodulatory potentials. Due to their strategic …
lymphocytes with enormous immunomodulatory potentials. Due to their strategic …
Activation-induced pyroptosis contributes to the loss of MAIT cells in chronic HIV-1 infected patients
P Xia, XD Xing, CX Yang, XJ Liao, FH Liu… - Military Medical …, 2022 - Springer
Background Mucosal-associated invariant T (MAIT) cells are systemically depleted in human
immunodeficiency virus type 1 (HIV-1) infected patients and are not replenished even after …
immunodeficiency virus type 1 (HIV-1) infected patients and are not replenished even after …
Mucosal-associated invariant T cells in infectious diseases of respiratory system: recent advancements and applications
X Lin, Y Wang, Y He - Journal of Inflammation, 2024 - Springer
Mucosal-associated invariant T (MAIT) cells are an atypical subset of T lymphocytes, which
have a highly conserved semi-constant αβ chain of T-cell receptor (TCR) and recognize …
have a highly conserved semi-constant αβ chain of T-cell receptor (TCR) and recognize …
MAIT cells are functionally impaired in a Mauritian cynomolgus macaque model of SIV and Mtb co-infection
AL Ellis, AJ Balgeman, EC Larson, MA Rodgers… - PLoS …, 2020 - journals.plos.org
Mucosal-associated invariant T (MAIT) cells can recognize and respond to some bacterially
infected cells. Several in vitro and in vivo models of Mycobacterium tuberculosis (Mtb) …
infected cells. Several in vitro and in vivo models of Mycobacterium tuberculosis (Mtb) …
Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection
MYH Lee, AA Upadhyay, H Walum, CN Chan… - PLoS …, 2021 - journals.plos.org
HIV associated immune activation (IA) is associated with increased morbidity in people
living with HIV (PLWH) on antiretroviral therapy, and remains a barrier for strategies aimed …
living with HIV (PLWH) on antiretroviral therapy, and remains a barrier for strategies aimed …
IL7RA single nucleotide polymorphisms are associated with the size and function of the MAIT cell population in treated HIV-1 infection
F Han, MY Gulam, Y Zheng, NS Zulhaimi… - Frontiers in …, 2022 - frontiersin.org
MAIT cells are persistently depleted and functionally exhausted in HIV-1-infected patients
despite long-term combination antiretroviral therapy (cART). IL-7 treatment supports MAIT …
despite long-term combination antiretroviral therapy (cART). IL-7 treatment supports MAIT …
MAIT cell loss and reconstitution in HIV-1 disease
Mucosa-associated invariant T (MAIT) cells are unconventional innate-like T cells that
recognize microbial riboflavin-related metabolites presented by the evolutionarily conserved …
recognize microbial riboflavin-related metabolites presented by the evolutionarily conserved …
HTNV infection induces activation and deficiency of CD8+MAIT cells in HFRS patients
Y Zhang, M Wang, X Zhang, K Tang… - Clinical and …, 2023 - academic.oup.com
Hantaan virus (HTNV) infection causes an epidemic of hemorrhagic fever with renal
syndrome (HFRS) mainly in Asia. Mucosal-associated invariant T (MAIT) cells are innate-like …
syndrome (HFRS) mainly in Asia. Mucosal-associated invariant T (MAIT) cells are innate-like …
Mouse models illuminate MAIT cell biology
H Wang, Z Chen, J McCluskey, AJ Corbett - Molecular immunology, 2021 - Elsevier
The field of mucosal-associated invariant T cell (MAIT) biology has grown rapidly since the
identification of the vitamin-B-based antigens recognised by these specialised T cells. Over …
identification of the vitamin-B-based antigens recognised by these specialised T cells. Over …
Enhanced IL-17 Producing and Maintained Cytolytic Effector Functions of Gut Mucosal CD161+CD8+ T Cells in SIV-Infected Rhesus Macaques
S Thirugnanam, EM Walker, F Schiro, PP Aye… - Viruses, 2023 - mdpi.com
Previous studies have indicated that the loss of CD161-expressing CD4+ Th17 cells is
linked to the progression of chronic HIV. These cells are significantly depleted in peripheral …
linked to the progression of chronic HIV. These cells are significantly depleted in peripheral …