Survivin, a member of the inhibitor of apoptosis (IAP) protein family that inhibits caspases
and blocks cell death, is highly expressed in most cancers and is associated with a poor …

Survivin, a member of the family of inhibitor of apoptosis proteins, functions as a key
regulator of mitosis and programmed cell death. Initially, survivin was described as an …

Acquisition of the ability to evade cellular suicide, or apoptosis, is one of the master switches
that contributes to cellular transformation and, ultimately, to invasive cancer. Much has been …

Survivin is a member of the inhibitor of apoptosis (IAP) gene family that has attracted
attention from several viewpoints of basic and translational research. Its cell cycle-regulated …

Various accumulating evidence suggests that survivin, a member of the inhibitor of
apoptosis (IAP) family, plays an important role in drug resistance and cancer cell survival in …

Survivin, an inhibitor of apoptosis protein, is highly expressed in most cancers and
associated with chemotherapy resistance, increased tumor recurrence, and shorter patient …

Survivin is an inhibitor of apoptosis protein, which is over-expressed in most tumors.
Aberrant expression of survivin and loss of wild-type p53 in many tumors prompted us to …

Microtubules are dynamic polymers that play crucial roles in a large number of cellular
functions. Their pivotal role in mitosis makes them a target for the development of anticancer …

Despite its genetic complexity and multifactoriality, two processes appear almost universally
compromised in cancer: the control of cell proliferation and the regulation of cell lifespan …

Previous studies have shown biological activity of thymoquinone, an active compound
extracted from Nigella sativa, in pancreatic cancer cells; however, preclinical animal studies …