In response to precision medicine: Current subcellular targeting strategies for cancer therapy

Z Li, J Zou, X Chen - Advanced Materials, 2023 - Wiley Online Library
Emerging as a potent anticancer treatment, subcellular targeted cancer therapy has drawn
increasing attention, bringing great opportunities for clinical application. Here, two targeting …

Obesity, type 2 diabetes, and cancer risk

T Scully, A Ettela, D LeRoith, EJ Gallagher - Frontiers in oncology, 2021 - frontiersin.org
Obesity and type 2 diabetes have both been associated with increased cancer risk and are
becoming increasingly prevalent. Metabolic abnormalities such as insulin resistance and …

[HTML][HTML] SCD1/FADS2 fatty acid desaturases equipoise lipid metabolic activity and redox-driven ferroptosis in ascites-derived ovarian cancer cells

Y Xuan, H Wang, MMH Yung, F Chen, WS Chan… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Malignant ascites in peritoneal metastases is a lipid-enriched microenvironment
and is frequently involved in the poor prognosis of epithelial ovarian cancer (EOC) …

Bacteriocin Production by Bacillus Species: Isolation, Characterization, and Application

V Mercado, J Olmos - Probiotics and Antimicrobial Proteins, 2022 - Springer
Antibiotic resistance is a problem that has been increasing lately; therefore, it is important to
find new alternatives to treat infections induced by pathogens that cannot be eliminated with …

Anticancer peptides mechanisms, simple and complex

P Norouzi, M Mirmohammadi, MHH Tehrani - Chemico-Biological …, 2022 - Elsevier
Peptide therapy has started since 1920s with the advent of insulin application, and now it
has emerged as a new approach in treatment of diseases including cancer. Using anti …

Current progresses and challenges of immunotherapy in triple-negative breast cancer

K Mediratta, S El-Sahli, V D'Costa, L Wang - Cancers, 2020 - mdpi.com
Simple Summary The breakthrough of immunotherapy in melanoma has generated a
glimmer of hope for lethal triple negative breast cancer (TNBC). This review summarizes the …

Phasor S-FLIM: a new paradigm for fast and robust spectral fluorescence lifetime imaging

L Scipioni, A Rossetta, G Tedeschi, E Gratton - Nature methods, 2021 - nature.com
Fluorescence lifetime imaging microscopy (FLIM) and spectral imaging are two broadly
applied methods for increasing dimensionality in microscopy. However, their combination is …

The relayed nuclear Overhauser effect in magnetization transfer and chemical exchange saturation transfer MRI

Y Zhou, C Bie, PCM van Zijl, NN Yadav - NMR in biomedicine, 2023 - Wiley Online Library
Magnetic resonance (MR) is a powerful technique for noninvasively probing molecular
species in vivo but suffers from low signal sensitivity. Saturation transfer (ST) MRI …

Challenges in cell membrane-camouflaged drug delivery systems: development strategies and future prospects

X Liu, X Zhong, C Li - Chinese Chemical Letters, 2021 - Elsevier
Extensive research has been performed on cell membrane camouflaged-based drug
delivery systems in recent years. Herein, we provide an overview of the challenges in …

Recent advances in organelle-targeted organic photosensitizers for efficient photodynamic therapy

M Dirak, CM Yenici, S Kolemen - Coordination Chemistry Reviews, 2024 - Elsevier
Photodynamic therapy (PDT) is a long known, FDA approved, and highly promising
therapeutic modality, which is still developing. Photosensitizers (PSs) are at the core of PDT …