[HTML][HTML] Fibroblast growth factor in diabetic foot ulcer: progress and therapeutic prospects

Y Liu, Y Liu, J Deng, W Li, X Nie - Frontiers in endocrinology, 2021 - frontiersin.org
Diabetic foot ulcer (DFU) is a combination of neuropathy and various degrees of peripheral
vasculopathy in diabetic patients resulting in lower extremity infection, ulcer formation, and …

Calcific aortic valve disease: mechanisms, prevention and treatment

LHM Moncla, M Briend, Y Bossé… - Nature Reviews Cardiology, 2023 - nature.com
Calcific aortic valve disease (CAVD) is the most common disorder affecting heart valves and
is characterized by thickening, fibrosis and mineralization of the aortic valve leaflets …

An engineered pseudo‐macrophage for rapid treatment of bacteria‐infected osteomyelitis via microwave‐excited anti‐infection and immunoregulation

J Fu, Y Li, Y Zhang, Y Liang, Y Zheng, Z Li… - Advanced …, 2021 - Wiley Online Library
Preventing deep bacterial infection and simultaneously enhancing osteogenic differentiation
are in great demand for osteomyelitis. Microwave (MW) dynamic therapy is attracting …

[HTML][HTML] Dietary intake regulates the circulating inflammatory monocyte pool

S Jordan, N Tung, M Casanova-Acebes, C Chang… - Cell, 2019 - cell.com
Caloric restriction is known to improve inflammatory and autoimmune diseases. However,
the mechanisms by which reduced caloric intake modulates inflammation are poorly …

[HTML][HTML] Collagen/hyaluronan based hydrogels releasing sulfated hyaluronan improve dermal wound healing in diabetic mice via reducing inflammatory macrophage …

S Hauck, P Zager, N Halfter, E Wandel, M Torregrossa… - Bioactive materials, 2021 - Elsevier
Sustained inflammation associated with dysregulated macrophage activation prevents
tissue formation and healing of chronic wounds. Control of inflammation and immune cell …

Reactive oxygen species–degradable polythioketal urethane foam dressings to promote porcine skin wound repair

P Patil, KA Russo, JT McCune, AC Pollins… - Science translational …, 2022 - science.org
Porous, resorbable biomaterials can serve as temporary scaffolds that support cell
infiltration, tissue formation, and remodeling of nonhealing skin wounds. Synthetic …

[HTML][HTML] Biomimetic nanoparticles to enhance the reverse cholesterol transport for selectively inhibiting development into foam cell in atherosclerosis

L Zhu, H Li, J Li, Y Zhong, S Wu, M Yan, S Ni… - Journal of …, 2023 - Springer
A disorder of cholesterol homeostasis is one of the main initiating factors in the progression
of atherosclerosis (AS). Metabolism and removal of excess cholesterol facilitates the …

[HTML][HTML] Macrophages in skin wounds: functions and therapeutic potential

SL Sim, S Kumari, S Kaur, K Khosrotehrani - Biomolecules, 2022 - mdpi.com
Macrophages regulate cutaneous wound healing by immune surveillance, tissue repair and
remodelling. The depletion of dermal macrophages during the early and middle stages of …

[HTML][HTML] Macrophages in periodontitis: a dynamic shift between tissue destruction and repair

L Yin, X Li, J Hou - Japanese Dental Science Review, 2022 - Elsevier
Periodontitis is a chronic inflammatory disease associated with a dysbiotic bacterial biofilm
in the subgingival environment that may disturb the balance between the oral microbiome …

[HTML][HTML] Epigenetic regulation of the PGE2 pathway modulates macrophage phenotype in normal and pathologic wound repair

FM Davis, LC Tsoi, R Wasikowski, A Joshi, C Wilke… - JCI insight, 2020 - ncbi.nlm.nih.gov
Macrophages are a primary immune cell involved in inflammation, and their cell plasticity
allows for transition from an inflammatory to a reparative phenotype and is critical for normal …