[HTML][HTML] Erythrocytes as carriers: From drug delivery to biosensors

L Koleva, E Bovt, F Ataullakhanov, E Sinauridze - Pharmaceutics, 2020 - mdpi.com
Drug delivery using natural biological carriers, especially erythrocytes, is a rapidly
developing field. Such erythrocytes can act as carriers that prolong the drug's action due to …

Approaches to erythrocyte-mediated drug delivery

M Magnani, L Rossi - Expert opinion on drug delivery, 2014 - Taylor & Francis
Introduction: Drug delivery by means of erythrocytes is becoming a growing field with
applications that in recent years have moved from the laboratory to the clinic. Several …

Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof

M Burnet, JH Guse, HJ Gutke, A Beck… - US Patent …, 2009 - Google Patents
T is a transportophore, L is a bond or a linker having a molecular weight up to 240 dalton, C
is a non-antibiotic therapeutic agent, and m is 1, 2, 3, 4, 5, 6, 7, or 8, in which the …

Activity of a novel combined antiretroviral therapy of gemcitabine and decitabine in a mouse model for HIV-1

CL Clouser, CM Holtz, M Mullett… - Antimicrobial agents …, 2012 - Am Soc Microbiol
The emergence of drug resistance threatens to limit the use of current anti-HIV-1 drugs and
highlights the need to expand the number of treatment options available for HIV-1-infected …

Liposomes as carriers of the antiretroviral agent dideoxycytidine-5′-triphosphate

C Oussoren, M Magnani, A Fraternale… - International journal of …, 1999 - Elsevier
The presence and replication of the human immunodeficiency virus (HIV) in cells of the
mononuclear phagocyte system (MPS) together with the preferential uptake of liposomes in …

Erythrocyte-mediated delivery of a new homodinucleotide active against human immunodeficiency virus and herpes simplex virus

L Rossi, S Serafini, L Cappellacci… - Journal of …, 2001 - academic.oup.com
Monocyte-derived macrophages (MDMs) play a central role in the pathogenesis of infection
by human immunodeficiency virus (HIV-1) and represent one of the main reservoirs of the …

Synthesis and targeted delivery of an azidothymidine homodinucleotide conferring protection to macrophages against retroviral infection.

M Magnani, A Casabianca… - Proceedings of the …, 1996 - National Acad Sciences
The infectivity and replication of human (HIV-1), feline (FIV), and murine (LP-BM5)
immunodeficiency viruses are all inhibited by several nucleoside analogues after …

Immunomodulatory effect of gold sodium thiomalate on murine acquired immunodeficiency syndrome

K Yamaguchi, H Ushijima, M Hisano… - Microbiology and …, 2001 - Wiley Online Library
Induction of IL‐2 production and increased expression of CD25 were observed in C57BL/10
mice after weekly treatment with gold sodium thiomalate (GST). LP‐BM5 murine leukemia …

Macrophage protection against human immunodeficiency virus or herpes simplex virus by red blood cell-mediated delivery of a heterodinucleotide of azidothymidine …

L Rossi, G Brandi, GF SCHIAVANO… - AIDS research and …, 1998 - liebertpub.com
Human herpesvirus (HSVs) are distributed worldwide and are among the most frequent
causes of viral infection in HIV-1-immunocompromised patients. Hence, therapeutic …

Method of identifying improved conjugates of biologically active compounds

M Burnet, JH Guse, G Kim, A Beck, G Tsotsou… - US Patent …, 2013 - Google Patents
This invention features a method of identifying a compound useful for enhancing efficacy of
a therapeutic agent. The method includes incubating a compound in blood cells; sepa rating …