The endocannabinoid system: a potential target for the treatment of various diseases

H Lowe, N Toyang, B Steele, J Bryant… - International journal of …, 2021 - mdpi.com
The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …

Cannabinoids, the endocannabinoid system, and pain: a review of preclinical studies

DP Finn, S Haroutounian, AG Hohmann, E Krane… - Pain, 2021 - journals.lww.com
This narrative review represents an output from the International Association for the Study of
Pain's global task force on the use of cannabis, cannabinoids, and cannabis-based …

Trends in use, pharmacology, and clinical applications of emerging herbal nutraceuticals

EM Williamson, X Liu, AA Izzo - British Journal of …, 2020 - Wiley Online Library
The nutraceuticals market is vast, encompassing many different products with inconsistent
levels of evidence available to support their use. This overview represents a Western …

Serotonin in animal cognition and behavior

J Bacqué-Cazenave, R Bharatiya, G Barrière… - International journal of …, 2020 - mdpi.com
Serotonin (5-hydroxytryptamine, 5-HT) is acknowledged as a major neuromodulator of
nervous systems in both invertebrates and vertebrates. It has been proposed for several …

Cannabidiol for pain treatment: focus on pharmacology and mechanism of action

J Mlost, M Bryk, K Starowicz - International journal of molecular sciences, 2020 - mdpi.com
Cannabis has a long history of medical use. Although there are many cannabinoids present
in cannabis, Δ9tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) are the two …

Immune responses regulated by cannabidiol

JM Nichols, BLF Kaplan - Cannabis and cannabinoid research, 2020 - liebertpub.com
Introduction: Cannabidiol (CBD) as Epidiolex®(GW Pharmaceuticals) was recently
approved by the US Food and Drug Administration (FDA) to treat rare forms of epilepsy in …

The polypharmacological effects of cannabidiol

J Castillo-Arellano, A Canseco-Alba, SJ Cutler, F León - Molecules, 2023 - mdpi.com
Cannabidiol (CBD) is a major phytocannabinoid present in Cannabis sativa (Linneo, 1753).
This naturally occurring secondary metabolite does not induce intoxication or exhibit the …

[HTML][HTML] Anxiolytic effects of repeated cannabidiol treatment in teenagers with social anxiety disorders

N Masataka - Frontiers in psychology, 2019 - frontiersin.org
Accumulated evidence indicates that cannabidiol (CBD), a nonpsychotomimetic and
nonaddictive main component of the Cannabis sativa plant, reverses anxiety-like behavior …

Analgesic effect of acetaminophen: a review of known and novel mechanisms of action

N Ohashi, T Kohno - Frontiers in Pharmacology, 2020 - frontiersin.org
Acetaminophen is one of the most commonly used analgesic agents for treating acute and
chronic pain. However, its metabolism is complex, and its analgesic mechanisms have not …

Cannabidiol treatment in hand osteoarthritis and psoriatic arthritis: a randomized, double-blind, placebo-controlled trial

J Vela, L Dreyer, KK Petersen, L Arendt-Nielsen… - Pain, 2022 - journals.lww.com
Cannabidiol (CBD) is increasingly used as analgesic medication although the recent
International Association for the Study of Pain Presidential Task Force on cannabis and …