As the leading infectious cause of death worldwide and the primary proximal cause of death
in individuals living with HIV, tuberculosis remains a global concern. Existing tuberculosis …

Background: Tuberculosis (TB) poses a severe public health challenge in China and
worldwide. This study evaluated the effects of age, period, and birth cohort on reported …

Tuberculosis (TB) still causes 1.5 million deaths globally each year. Over recent decades,
slow and uneven declines in TB incidence have resulted in a falling prevalence of TB …

Background Whole genome sequencing provides better delineation of transmission clusters
in Mycobacterium tuberculosis than traditional methods. However, its ability to reveal …

Background With improved tuberculosis (TB) control programs, the incidence of TB in China
declined dramatically over the past few decades, but recently the rate of decrease has …

Comparing the pathogen genomes from several cases of an infectious disease has the
potential to help us understand and control outbreaks. Many methods exist to reconstruct a …

Spatially targeted interventions may be effective alternatives to individual or population-
based prevention strategies against tuberculosis (TB). However, their efficacy may depend …

Background Population movement could extend multidrug-resistant tuberculosis (MDR-TB)
transmission and complicate its global prevalence. We sought to identify the high-risk …

Objectives Our aim was to assess the ability of the Whole-genome sequencing (WGS) in
predicting drug resistance profile of multidrug-resistant mycobacterium tuberculosis (MDR …

Background MPT64 is a key protein used for Mycobacterium tuberculosis (MTB) complex
strain identification. We describe protracted transmission of an MPT64 negative MTB strain …