Purpose of review This article reviews the genetics of multiple sclerosis (MS), as well as intra-
familial concordance and clinical correlations between different members of a family …

MicroRNAs (miRNAs) are a recently discovered group of small noncoding RNAs that
regulate gene expression post-transcriptionally. They are highly expressed in cells of the …

The last 20 years have seen major progress in the treatment of relapsing–remitting multiple
sclerosis (RRMS) using a variety of drugs targeting immune dysfunction. In contrast, all …

A genetic contribution to MS pathogenesis has been proven ever since the association with
the HLA-DR2 locus was discovered more than 30 years ago. The search for additional MS …

Multiple sclerosis (MS) is characterized by inflammation, axonal and oligodendrocyte
pathology and progressive neurological disability. Epidemiologic data indicate that MS may …

Molecular motors are cellular components involved in the intracellular transport of
organelles and materials to ensure cell homeostasis. This is particularly relevant in neurons …

Multiple sclerosis (MS) patients are classified as either having relapsing onset or
progressive onset disease, also known as primary progressive MS (PPMS). Relative to …

Statistical equivalence methods have been in development since the late 1980s in order to
provide an appropriate statistical methodology to address nondifferences in biological …

Objective A recent collaborative genome-wide association study replicated a large number
of susceptibility loci and identified novel loci. This increase in known multiple sclerosis (MS) …

Монография посвящена современным аспектам нейроиммунных механизмов
формирования патологического процесса в нервной системе при рассеянном склерозе …