Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …

Living organisms use a large repertoire of anabolic and catabolic reactions to maintain their
physiological body functions, many of which include oxidation and reduction of substrates …

Peroxisome biogenesis disorders in the Zellweger spectrum (PBD-ZSD) are a
heterogeneous group of genetic disorders caused by mutations in PEX genes responsible …

Zellweger spectrum disorders (ZSDs) represent the major subgroup within the peroxisomal
biogenesis disorders caused by defects in PEX genes. The Zellweger spectrum is a clinical …

Peroxisomes are essential metabolic organelles, well known for their roles in the
metabolism of complex lipids and reactive ionic species. In the past 10 years, peroxisomes …

Background & Aims Severe malnutrition in young children is associated with signs of hepatic
dysfunction such as steatosis and hypoalbuminemia, but its etiology is unknown …

In recent decades, the role of the peroxisome in physiology and disease conditions has
become increasingly important. Together with the mitochondria and other cellular …

Translational readthrough gives rise to low abundance proteins with C-terminal extensions
beyond the stop codon. To identify functional translational readthrough, we estimated the …

In order to optimize their multiple cellular functions, peroxisomes must collaborate and
communicate with the surrounding organelles. A common way of communication between …

Cells of an organism face with various types of insults during their lifetime. Exposure to
toxins, metabolic problems, ischaemia/reperfusion, physical trauma, genetic diseases …