The generation of the components that make up the embryonic body axis, such as the spinal
cord and vertebral column, takes place in an anterior-to-posterior (head-to-tail) direction …

The developmental origin of vascular smooth muscle cells (VSMCs) has been increasingly
recognized as a major determinant for regional susceptibility or resistance to vascular …

The enteric nervous system (ENS) is derived from both the vagal and sacral component of
the neural crest (NC). Here, we present the derivation of sacral ENS precursors from human …

Pericytes play essential roles in blood–brain barrier (BBB) integrity and dysfunction or
degeneration of pericytes is implicated in a set of neurological disorders although the …

Neurofibromatosis type 1 (NF1) is a common tumor predisposition syndrome caused by NF1
gene mutation, in which affected patients develop Schwann cell lineage peripheral nerve …

Calvarial bone is one of the most complex sequences of developmental events in
embryology, featuring a uniquely transient, pluripotent stem cell-like population known as …

The neural crest (NC) is a multipotent embryonic cell population that generates distinct cell
types in an axial position-dependent manner. The production of NC cells from human …

The neural crest is a fascinating embryonic population unique to vertebrates that is endowed
with remarkable differentiation capacity. Thought to originate from ectodermal tissue, neural …

Mesenchymal stem/stromal cells (MSCs) are adult multipotent stem cells. Here, we induced
MSCs from human induced pluripotent stem cells (iPSCs) via a neural crest cell (NCC) …

Schwann cells are glial cells of the peripheral nervous system. They exist in several
subtypes and perform a variety of functions in nerves. Their derivation and culture in vitro are …