A comprehensive review on the role of the gut microbiome in human neurological disorders
SG Sorboni, HS Moghaddam… - Clinical microbiology …, 2022 - Am Soc Microbiol
The human body is full of an extensive number of commensal microbes, consisting of
bacteria, viruses, and fungi, collectively termed the human microbiome. The initial …
bacteria, viruses, and fungi, collectively termed the human microbiome. The initial …
Maternal immune activation and neuroinflammation in human neurodevelopmental disorders
Maternal health during pregnancy plays a major role in shaping health and disease risks in
the offspring. The maternal immune activation hypothesis proposes that inflammatory …
the offspring. The maternal immune activation hypothesis proposes that inflammatory …
[HTML][HTML] Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation
H Hodges, C Fealko, N Soares - Translational pediatrics, 2020 - ncbi.nlm.nih.gov
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits
in social communication and the presence of restricted interests and repetitive behaviors …
in social communication and the presence of restricted interests and repetitive behaviors …
Genetic causes and modifiers of autism spectrum disorder
L Rylaarsdam, A Guemez-Gamboa - Frontiers in cellular …, 2019 - frontiersin.org
Autism Spectrum Disorder (ASD) is one of the most prevalent neurodevelopmental
disorders, affecting an estimated 1 in 59 children. ASD is highly genetically heterogeneous …
disorders, affecting an estimated 1 in 59 children. ASD is highly genetically heterogeneous …
Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder
INTRODUCTION Our understanding of the pathophysiology of psychiatric disorders,
including autism spectrum disorder (ASD), schizophrenia (SCZ), and bipolar disorder (BD) …
including autism spectrum disorder (ASD), schizophrenia (SCZ), and bipolar disorder (BD) …
The contribution of environmental exposure to the etiology of autism spectrum disorder
Autism spectrum disorder (ASD) is a neurodevelopmental condition of heterogeneous
etiology. While it is widely recognized that genetic and environmental factors and their …
etiology. While it is widely recognized that genetic and environmental factors and their …
Innate immunity at the crossroads of healthy brain maturation and neurodevelopmental disorders
KE Zengeler, JR Lukens - Nature Reviews Immunology, 2021 - nature.com
The immune and nervous systems have unique developmental trajectories that individually
build intricate networks of cells with highly specialized functions. These two systems have …
build intricate networks of cells with highly specialized functions. These two systems have …
Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications
CC Jiang, LS Lin, S Long, XY Ke, K Fukunaga… - Signal transduction and …, 2022 - nature.com
Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …
Microglia and neurodevelopmental disorders
Mounting evidence indicates that microglia, which are the resident immune cells of the brain,
play critical roles in a diverse array of neurodevelopmental processes required for proper …
play critical roles in a diverse array of neurodevelopmental processes required for proper …
Autism spectrum disorders and the gut microbiota
A Fattorusso, L Di Genova, GB Dell'Isola, E Mencaroni… - Nutrients, 2019 - mdpi.com
In recent years, there has been an emerging interest in the possible role of the gut
microbiota as a co-factor in the development of autism spectrum disorders (ASDs), as many …
microbiota as a co-factor in the development of autism spectrum disorders (ASDs), as many …