Human tumors often trigger a hypercoagulable state that promotes hemostatic
complications, including venous thromboembolism. The recent application of systems …

FAK is a tyrosine kinase overexpressed in cancer cells and plays an important role in the
progression of tumors to a malignant phenotype. Except for its typical role as a cytoplasmic …

High-grade gliomas, the most common and aggressive primary brain tumors, are
characterized by a complex tumor microenvironment (TME). Among the immune cells …

SLIT2 is a secreted polypeptide that guides migration of cells expressing Roundabout 1 and
2 (ROBO1 and ROBO2) receptors. Herein, we investigated SLIT2/ROBO signaling effects in …

Abstract Background Microtubes (MTs), cytoplasmic extensions of glioma cells, are
important cell communication structures promoting invasion and treatment resistance …

Glioblastoma, a subset of aggressive brain tumors, deploy several means to increase blood
vessel supply dedicated to the tumor mass. This includes typical program borrowed from …

Background Glioblastoma is the most common and aggressive type of primary brain tumor,
as most patients succumb to the disease less than two years after diagnosis. Critically …

Glioblastoma (GBM) is the most common and fatal primary malignant brain tumor. Despite
advances in the understanding of the biology of gliomas, little has changed in the treatment …

In this study, we investigated the regulatory role of exosomal microRNA-944 (miR-944)
derived from glioma stem cells (GSCs) in glioma progression and angiogenesis …

Glioblastoma (GBM) remains the most malignant primary brain tumor, with a median survival
rarely exceeding 2 years. Tumor heterogeneity and an immunosuppressive …