The continuous flow of new research articles on MDR-TB diagnosis, treatment, prevention
and rehabilitation requires frequent update of existing guidelines. This review is aimed at …

Tuberculosis is the leading cause of deaths from an infectious disease worldwide. WHO's
End TB Strategy is falling short of several 2020 targets. Undernutrition is the leading …

BACKGROUND: Optimal drug dosing is important to ensure adequate response to
treatment, prevent development of drug resistance and reduce drug toxicity. The aim of …

Tuberculosis (TB) is still the number one cause of death due to an infectious disease.
Pharmacokinetics and pharmacodynamics of anti-TB drugs are key in the optimization of TB …

Background Suboptimal exposure to antituberculosis (anti-TB) drugs has been associated
with unfavourable treatment outcomes. We aimed to investigate estimates and determinants …

Background Prospective studies correlating pharmacokinetic/pharmacodynamic (PK/PD)
indices to clinical responses are urgently needed. This study aimed to find clinically relevant …

Background Understanding the impact of drug exposure and susceptibility on treatment
response of multidrug-resistant tuberculosis (MDR-TB) will help to optimise treatment. This …

Introduction Therapeutic drug monitoring (TDM) has been recommended for treatment
optimization in tuberculosis (TB) but is only is used in certain countries eg USA, Germany …

Aims The purpose of the study was to assess the status of emerging therapeutic drug
monitoring (TDM) of anti‐infective agents in Australian hospitals. Methods A nationwide …

Abstract Background and Objective Quantifying exposure to drugs for personalized dose
adjustment is of critical importance in patients with tuberculosis who may be at risk of …